ENSG00000079308


Homo sapiens

Features
Gene ID: ENSG00000079308
  
Biological name :TNS1
  
Synonyms : Q9HBL0 / tensin 1 / TNS1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q35
Gene start: 217799588
Gene end: 218010421
  
Corresponding Affymetrix probe sets: 218863_s_at (Human Genome U133 Plus 2.0 Array)   218864_at (Human Genome U133 Plus 2.0 Array)   221246_x_at (Human Genome U133 Plus 2.0 Array)   221747_at (Human Genome U133 Plus 2.0 Array)   221748_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000400383
Ensembl peptide - ENSP00000395615
Ensembl peptide - ENSP00000404477
Ensembl peptide - ENSP00000493967
Ensembl peptide - ENSP00000484271
Ensembl peptide - ENSP00000480559
Ensembl peptide - ENSP00000414704
Ensembl peptide - ENSP00000411349
Ensembl peptide - ENSP00000408724
Ensembl peptide - ENSP00000406016
Ensembl peptide - ENSP00000405460
Ensembl peptide - ENSP00000171887
Ensembl peptide - ENSP00000308321
Ensembl peptide - ENSP00000393925
Ensembl peptide - ENSP00000394171
NCBI entrez gene - 7145     See in Manteia.
OMIM - 600076
RefSeq - XM_017004817
RefSeq - XM_017004802
RefSeq - XM_017004803
RefSeq - XM_017004804
RefSeq - XM_017004805
RefSeq - XM_017004806
RefSeq - XM_017004807
RefSeq - XM_017004808
RefSeq - XM_017004809
RefSeq - XM_017004810
RefSeq - XM_017004811
RefSeq - XM_017004812
RefSeq - XM_017004813
RefSeq - XM_017004814
RefSeq - XM_017004815
RefSeq - XM_017004816
RefSeq - NM_001308022
RefSeq - NM_001308023
RefSeq - NM_022648
RefSeq - XM_011511712
RefSeq - XM_011511713
RefSeq - XM_011511715
RefSeq - XM_011511723
RefSeq - XM_011511728
RefSeq - XM_017004801
RefSeq Peptide - NP_072174
RefSeq Peptide - NP_001294951
RefSeq Peptide - NP_001294952
swissprot - E7EMG1
swissprot - C9JZT0
swissprot - C9JI43
swissprot - C9JFT7
swissprot - E9PGF5
swissprot - H0Y4U1
swissprot - H7C3Z4
swissprot - Q9HBL0
swissprot - A0A087WWW7
swissprot - C9J8K5
swissprot - E9PF55
swissprot - E7ERH1
Ensembl - ENSG00000079308
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tns1aENSDARG00000078842Danio rerio
 tns1bENSDARG00000020845Danio rerio
 TNS1ENSGALG00000041013Gallus gallus
 Tns1ENSMUSG00000055322Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TNS3 / Q68CZ2 / tensin 3ENSG0000013620540
TNS2 / Q63HR2 / tensin 2ENSG0000011107731
TNS4 / Q8IZW8 / tensin 4ENSG0000013174615
GAK / O14976 / cyclin G associated kinaseENSG0000017895012
DNAJC6 / O75061 / DnaJ heat shock protein family (Hsp40) member C6ENSG0000011667510
PTEN / P60484 / phosphatase and tensin homologENSG000001718627
TPTE2 / Q6XPS3 / transmembrane phosphoinositide 3-phosphatase and tensin homolog 2ENSG000001329585
TPTE / P56180 / transmembrane phosphatase with tensin homologyENSG000002743915


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR013625  Tensin/EPS8 phosphotyrosine-binding domain
 IPR014020  Tensin phosphatase, C2 domain
 IPR029021  Protein-tyrosine phosphatase-like
 IPR029023  Tensin-type phosphatase domain
 IPR033929  Tensin, phosphotyrosine-binding domain
 IPR035012  Tensin-like, SH2 domain
 IPR035892  C2 domain superfamily
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007044 cell-substrate junction assembly IEA
 biological_processGO:0010761 fibroblast migration IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005925 focal adhesion IDA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030055 cell-substrate junction IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr