ENSG00000081026


Homo sapiens

Features
Gene ID: ENSG00000081026
  
Biological name :MAGI3
  
Synonyms : MAGI3 / membrane associated guanylate kinase, WW and PDZ domain containing 3 / Q5TCQ9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p13.2
Gene start: 113390749
Gene end: 113685923
  
Corresponding Affymetrix probe sets: 224307_x_at (Human Genome U133 Plus 2.0 Array)   226770_at (Human Genome U133 Plus 2.0 Array)   230409_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358628
Ensembl peptide - ENSP00000358630
Ensembl peptide - ENSP00000304604
Ensembl peptide - ENSP00000358624
NCBI entrez gene - 260425     See in Manteia.
OMIM - 615943
RefSeq - XM_017000975
RefSeq - NM_001142782
RefSeq - NM_152900
RefSeq - XM_005270737
RefSeq - XM_011541208
RefSeq - XM_017000974
RefSeq Peptide - NP_001136254
RefSeq Peptide - NP_690864
swissprot - A0A024R0H3
swissprot - Q5TCQ9
swissprot - A0A024R0E9
Ensembl - ENSG00000081026
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 magi3aENSDARG00000101869Danio rerio
 magi3bENSDARG00000025974Danio rerio
 MAGI3ENSGALG00000001816Gallus gallus
 Magi3ENSMUSG00000052539Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAGI2 / Q86UL8 / membrane associated guanylate kinase, WW and PDZ domain containing 2ENSG0000018739145
MAGI1 / Q96QZ7 / membrane associated guanylate kinase, WW and PDZ domain containing 1ENSG0000015127639
SAV1 / Q9H4B6 / salvador family WW domain containing protein 1ENSG000001517487
MAGIX / MAGI family member, X-linkedENSG000002693136


Protein motifs (from Interpro)
Interpro ID Name
 IPR001202  WW domain
 IPR001478  PDZ domain
 IPR008144  Guanylate kinase-like domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR020590  Guanylate kinase, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030035  Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3
 IPR036020  WW domain superfamily
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process NAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0035556 intracellular signal transduction NAS
 biological_processGO:0046037 GMP metabolic process IEA
 biological_processGO:0046328 regulation of JNK cascade IEA
 biological_processGO:0046710 GDP metabolic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane NAS
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004385 guanylate kinase activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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