ENSG00000082397


Homo sapiens

Features
Gene ID: ENSG00000082397
  
Biological name :EPB41L3
  
Synonyms : EPB41L3 / erythrocyte membrane protein band 4.1 like 3 / Q9Y2J2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: -1
Band: p11.31
Gene start: 5392381
Gene end: 5630700
  
Corresponding Affymetrix probe sets: 206710_s_at (Human Genome U133 Plus 2.0 Array)   211776_s_at (Human Genome U133 Plus 2.0 Array)   212681_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464336
Ensembl peptide - ENSP00000464148
Ensembl peptide - ENSP00000464533
Ensembl peptide - ENSP00000489681
Ensembl peptide - ENSP00000489405
Ensembl peptide - ENSP00000488647
Ensembl peptide - ENSP00000488626
Ensembl peptide - ENSP00000488095
Ensembl peptide - ENSP00000488037
Ensembl peptide - ENSP00000487915
Ensembl peptide - ENSP00000487786
Ensembl peptide - ENSP00000487780
Ensembl peptide - ENSP00000464570
Ensembl peptide - ENSP00000341138
Ensembl peptide - ENSP00000343158
Ensembl peptide - ENSP00000382981
Ensembl peptide - ENSP00000441174
Ensembl peptide - ENSP00000442091
Ensembl peptide - ENSP00000461937
Ensembl peptide - ENSP00000462338
Ensembl peptide - ENSP00000462692
Ensembl peptide - ENSP00000462783
Ensembl peptide - ENSP00000463122
Ensembl peptide - ENSP00000463289
Ensembl peptide - ENSP00000463707
Ensembl peptide - ENSP00000464020
NCBI entrez gene - 23136     See in Manteia.
OMIM - 605331
RefSeq - XM_017025660
RefSeq - XM_017025633
RefSeq - XM_017025634
RefSeq - XM_017025635
RefSeq - XM_017025636
RefSeq - XM_017025637
RefSeq - XM_017025638
RefSeq - XM_017025639
RefSeq - XM_017025640
RefSeq - XM_017025641
RefSeq - XM_017025642
RefSeq - XM_017025643
RefSeq - XM_017025644
RefSeq - XM_017025645
RefSeq - XM_017025646
RefSeq - XM_017025647
RefSeq - XM_017025648
RefSeq - XM_017025649
RefSeq - XM_017025650
RefSeq - XM_017025651
RefSeq - XM_017025652
RefSeq - XM_017025653
RefSeq - XM_017025654
RefSeq - XM_017025655
RefSeq - XM_017025656
RefSeq - XM_017025657
RefSeq - XM_017025658
RefSeq - XM_017025659
RefSeq - NM_001281533
RefSeq - NM_001281534
RefSeq - NM_001281535
RefSeq - NM_001330557
RefSeq - NM_012307
RefSeq - XM_011525623
RefSeq - XM_011525626
RefSeq - XM_011525628
RefSeq - XM_011525632
RefSeq - XM_011525634
RefSeq - XM_011525637
RefSeq - XM_017025618
RefSeq - XM_017025619
RefSeq - XM_017025620
RefSeq - XM_017025621
RefSeq - XM_017025622
RefSeq - XM_017025623
RefSeq - XM_017025624
RefSeq - XM_017025625
RefSeq - XM_017025626
RefSeq - XM_017025627
RefSeq - XM_017025628
RefSeq - XM_017025629
RefSeq - XM_017025630
RefSeq - XM_017025631
RefSeq - XM_017025632
RefSeq Peptide - NP_036439
RefSeq Peptide - NP_001268464
RefSeq Peptide - NP_001317486
RefSeq Peptide - NP_001268462
RefSeq Peptide - NP_001268463
swissprot - A0A0J9YWN0
swissprot - A0A0J9YWE1
swissprot - A0A0J9YW31
swissprot - A0A0J9YW26
swissprot - A0A0A0MSA4
swissprot - J3KRD1
swissprot - J3KS70
swissprot - J3KT37
swissprot - A8K968
swissprot - J3QKY2
swissprot - J3QLU5
swissprot - J3QR33
swissprot - J3QRQ6
swissprot - J3QS55
swissprot - J3QS83
swissprot - Q9Y2J2
swissprot - A0A0A0MRA8
swissprot - J3QKK4
swissprot - A0A1B0GTF8
swissprot - A0A0U1RR92
swissprot - A0A0J9YY18
swissprot - A0A0J9YWS4
Ensembl - ENSG00000082397
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 epb41l3aENSDARG00000002255Danio rerio
 epb41l3bENSDARG00000019917Danio rerio
 EPB41L3ENSGALG00000038678Gallus gallus
 Q9WV92ENSMUSG00000024044Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O43491 / EPB41L2 / erythrocyte membrane protein band 4.1 like 2ENSG0000007981943
Q9H4G0 / EPB41L1 / erythrocyte membrane protein band 4.1 like 1ENSG0000008836741
EPB41 / P11171 / erythrocyte membrane protein band 4.1ENSG0000015902338
PTPN4 / P29074 / protein tyrosine phosphatase, non-receptor type 4ENSG0000008817921
Q9H329 / EPB41L4B / erythrocyte membrane protein band 4.1 like 4BENSG0000009520318
Q9HCM4 / EPB41L5 / erythrocyte membrane protein band 4.1 like 5ENSG0000011510918
Q9HCS5 / EPB41L4A / erythrocyte membrane protein band 4.1 like 4AENSG0000012959518
PTPN3 / P26045 / protein tyrosine phosphatase, non-receptor type 3ENSG0000007015917
FRMD3 / A2A2Y4 / FERM domain containing 3ENSG0000017215916
FRMD5 / Q7Z6J6 / FERM domain containing 5ENSG0000017187715


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR000798  Ezrin/radixin/moesin-like
 IPR007477  SAB domain
 IPR008379  Band 4.1, C-terminal
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR014847  FERM adjacent (FA)
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR030691  Band 4.1-like protein 3
 IPR035963  FERM superfamily, second domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0002175 protein localization to paranode region of axon ISS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0007016 cytoskeletal anchoring at plasma membrane IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0008360 regulation of cell shape ISS
 biological_processGO:0030865 cortical cytoskeleton organization TAS
 biological_processGO:0030866 cortical actin cytoskeleton organization IEA
 biological_processGO:0030913 paranodal junction assembly ISS
 biological_processGO:0031032 actomyosin structure organization IBA
 biological_processGO:0043217 myelin maintenance ISS
 biological_processGO:0048812 neuron projection morphogenesis ISS
 biological_processGO:0071205 protein localization to juxtaparanode region of axon ISS
 biological_processGO:0072659 protein localization to plasma membrane ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030673 axolemma ISS
 cellular_componentGO:0033270 paranode region of axon ISS
 cellular_componentGO:0044224 juxtaparanode region of axon ISS
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008092 cytoskeletal protein binding IEA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000147044 CASK / O14936 / calcium/calmodulin dependent serine protein kinase  / complex / reaction






 

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