ENSG00000085449


Homo sapiens

Features
Gene ID: ENSG00000085449
  
Biological name :WDFY1
  
Synonyms : Q8IWB7 / WDFY1 / WD repeat and FYVE domain containing 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q36.1
Gene start: 223855716
Gene end: 223945387
  
Corresponding Affymetrix probe sets: 224800_at (Human Genome U133 Plus 2.0 Array)   233559_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000233055
Ensembl peptide - ENSP00000395416
NCBI entrez gene - 57590     See in Manteia.
RefSeq - NM_020830
RefSeq Peptide - NP_065881
swissprot - C9JJ54
swissprot - A0A024R488
swissprot - Q8IWB7
Ensembl - ENSG00000085449
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wdfy1ENSDARG00000005425Danio rerio
 WDFY1ENSGALG00000005158Gallus gallus
 Wdfy1ENSMUSG00000073643Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WDFY2 / Q96P53 / WD repeat and FYVE domain containing 2ENSG0000013966860


Protein motifs (from Interpro)
Interpro ID Name
 IPR000306  FYVE zinc finger
 IPR001680  WD40 repeat
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017455  Zinc finger, FYVE-related
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0034141 positive regulation of toll-like receptor 3 signaling pathway IMP
 biological_processGO:0034145 positive regulation of toll-like receptor 4 signaling pathway IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005545 1-phosphatidylinositol binding IDA
 molecular_functionGO:0008270 zinc ion binding NAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr