ENSG00000086015


Homo sapiens

Features
Gene ID: ENSG00000086015
  
Biological name :MAST2
  
Synonyms : MAST2 / microtubule associated serine/threonine kinase 2 / Q6P0Q8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p34.1
Gene start: 45786987
Gene end: 46036124
  
Corresponding Affymetrix probe sets: 211593_s_at (Human Genome U133 Plus 2.0 Array)   215660_s_at (Human Genome U133 Plus 2.0 Array)   215661_at (Human Genome U133 Plus 2.0 Array)   215903_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361079
Ensembl peptide - ENSP00000354671
Ensembl peptide - ENSP00000361078
NCBI entrez gene - 23139     See in Manteia.
OMIM - 612257
RefSeq - XM_017000755
RefSeq - NM_001319245
RefSeq - NM_001324320
RefSeq - NM_001324321
RefSeq - NM_015112
RefSeq - XM_011541065
RefSeq - XM_011541067
RefSeq - XM_011541068
RefSeq - XM_011541069
RefSeq - XM_017000752
RefSeq - XM_017000753
RefSeq - XM_017000754
RefSeq - XM_005270655
RefSeq - XM_005270656
RefSeq - XM_006710477
RefSeq - XM_011541059
RefSeq - XM_011541061
RefSeq - XM_011541062
RefSeq - XM_011541063
RefSeq - XM_011541064
RefSeq Peptide - NP_001306174
RefSeq Peptide - NP_001311249
RefSeq Peptide - NP_001311250
RefSeq Peptide - NP_055927
swissprot - Q6P0Q8
swissprot - V9GXZ1
swissprot - E7ERL6
Ensembl - ENSG00000086015
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mast2ENSDARG00000074311Danio rerio
 Mast2ENSMUSG00000003810Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAST4 / O15021 / microtubule associated serine/threonine kinase family member 4ENSG0000006902058
MAST1 / Q9Y2H9 / microtubule associated serine/threonine kinase 1ENSG0000010561355
MAST3 / O60307 / microtubule associated serine/threonine kinase 3ENSG0000009930845
MASTL / Q96GX5 / microtubule associated serine/threonine kinase likeENSG000001205398


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR001478  PDZ domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR015022  Microtubule-associated serine/threonine-protein kinase, domain
 IPR023142  Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily
 IPR028779  Microtubule-associated serine/threonine-protein kinase 2
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007010 cytoskeleton organization IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0045075 regulation of interleukin-12 biosynthetic process IEA
 biological_processGO:0048515 spermatid differentiation ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IBA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019902 phosphatase binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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