ENSG00000092208


Homo sapiens
complexGEMIN2proteinspliceosomalassemblyrnasplicingsnrnpnucleusgem-associatedgeminbrrviatransesterificationreactionsmrnaprocessingimportintracellularnucleoplasmnucleoluscytoplasmcytosolnuclearbodysmnsmn-smgeminicoiledbodiesbinding

Features
Gene ID: ENSG00000092208
  
Biological name :GEMIN2
  
Synonyms : GEMIN2 / gem nuclear organelle associated protein 2 / O14893
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q21.1
Gene start: 39114223
Gene end: 39136973
  
Corresponding Affymetrix probe sets: 205063_at (Human Genome U133 Plus 2.0 Array)   210779_x_at (Human Genome U133 Plus 2.0 Array)   211114_x_at (Human Genome U133 Plus 2.0 Array)   211115_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000474979
Ensembl peptide - ENSP00000436065
Ensembl peptide - ENSP00000436854
Ensembl peptide - ENSP00000250379
Ensembl peptide - ENSP00000308533
Ensembl peptide - ENSP00000379548
Ensembl peptide - ENSP00000416827
Ensembl peptide - ENSP00000431500
Ensembl peptide - ENSP00000434048
NCBI entrez gene - 8487     See in Manteia.
OMIM - 602595
RefSeq - XM_017021709
RefSeq - NM_001009182
RefSeq - NM_001009183
RefSeq - NM_003616
RefSeq Peptide - NP_001009182
RefSeq Peptide - NP_001009183
RefSeq Peptide - NP_003607
swissprot - H0YCF4
swissprot - H0YDP6
swissprot - O14893
swissprot - H0YEL0
swissprot - S4R421
swissprot - G5EA29
Ensembl - ENSG00000092208
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gemin2ENSDARG00000015638Danio rerio
 GEMIN2ENSGALG00000010154Gallus gallus
 Gemin2ENSMUSG00000060121Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR017364  Gem-associated protein 2
 IPR035426  Gemin2/Brr1


Gene Ontology (GO)
nitrogen compound metabolic processcellular component organizationcellular component biogenesiscellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular localizationnitrogen compound metabolic processcellular component organizationcellular component biogenesiscellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular localizationnitrogen compound metabolic processcellular component organizationcellular component biogenesiscellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular localizationnitrogen compound metabolic processcellular component organizationcellular component biogenesiscellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular localizationnitrogen compound metabolic processcellular component organizationcellular component biogenesiscellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular localizationnitrogen compound metabolic processcellular component organizationcellular component biogenesiscellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular localizationnitrogen compound metabolic processcellular component organizationcellular component biogenesiscellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular localizationnitrogen compound metabolic processcellular component organizationcellular component biogenesiscellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular localizationnitrogen compound metabolic processcellular component organizationcellular component biogenesiscellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular localizationnitrogen compound metabolic processcellular component organizationcellular component biogenesiscellular metabolic processprimary metabolic processorganic substance metabolic processestablishment of localizationcellular localizationnitrogen compoundnitrogen compound metabolic processcellular componencellular component organizationcellular componencellular component biogenesiscellular metabolicellular metabolic processprimary metabolicprimary metabolic processorganic substanceorganic substance metabolic processestablishment of establishment of localizationcellular localizacellular localization
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0000245 spliceosomal complex assembly IEA
 biological_processGO:0000375 RNA splicing, via transesterification reactions TAS
 biological_processGO:0000387 spliceosomal snRNP assembly IEA
 biological_processGO:0006397 mRNA processing TAS
 biological_processGO:0008380 RNA splicing TAS
 biological_processGO:0051170 import into nucleus TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0032797 SMN complex IDA
 cellular_componentGO:0034719 SMN-Sm protein complex IDA
 cellular_componentGO:0097504 Gemini of coiled bodies IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
snRNP Assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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