ENSG00000099995


Homo sapiens

Features
Gene ID: ENSG00000099995
  
Biological name :SF3A1
  
Synonyms : Q15459 / SF3A1 / splicing factor 3a subunit 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q12.2
Gene start: 30331988
Gene end: 30356947
  
Corresponding Affymetrix probe sets: 201356_at (Human Genome U133 Plus 2.0 Array)   201357_s_at (Human Genome U133 Plus 2.0 Array)   216457_s_at (Human Genome U133 Plus 2.0 Array)   227516_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000397267
Ensembl peptide - ENSP00000412715
Ensembl peptide - ENSP00000400862
Ensembl peptide - ENSP00000215793
NCBI entrez gene - 10291     See in Manteia.
OMIM - 605595
RefSeq - NM_005877
RefSeq Peptide - NP_005868
swissprot - H7C1L2
swissprot - A0A024R1K8
swissprot - Q15459
swissprot - F8WB66
swissprot - F8WC79
Ensembl - ENSG00000099995
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sf3a1ENSDARG00000041887Danio rerio
 SF3A1ENSGALG00000007937Gallus gallus
 Sf3a1ENSMUSG00000002129Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000061  SWAP/Surp
 IPR000626  Ubiquitin domain
 IPR022030  Splicing factor 3A subunit 1
 IPR029071  Ubiquitin-like domain superfamily
 IPR035563  Splicing factor 3A subunit 1, ubiquitin domain
 IPR035967  SWAP/Surp superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IBA
 biological_processGO:0000389 mRNA 3"-splice site recognition TAS
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0006397 mRNA processing IMP
 biological_processGO:0008380 RNA splicing IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IDA
 cellular_componentGO:0005684 U2-type spliceosomal complex IDA
 cellular_componentGO:0005686 U2 snRNP IDA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0071004 U2-type prespliceosome IBA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000104897 SF3A2 / Q15428 / splicing factor 3a subunit 2  / complex
 ENSG00000183431 SF3A3 / Q12874 / splicing factor 3a subunit 3  / complex






 

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