Manteia

ENSG00000100078

Homo sapiens

Features

Gene ID:	ENSG00000100078

Biological name :	PLA2G3

Synonyms :	phospholipase A2 group III / PLA2G3 / Q9NZ20

Possible biological names infered from orthology :

Species:	Homo sapiens

Chr. number:	22
Strand:	-1
Band:	q12.2
Gene start:	31134809
Gene end:	31140607

Corresponding Affymetrix probe sets:	220780_at (Human Genome U133 Plus 2.0 Array)

Cross references:	Ensembl peptide - ENSP00000215885 NCBI entrez gene - 50487 See in Manteia. OMIM - 611651 RefSeq - XM_011530205 RefSeq - NM_015715 RefSeq - XM_011530204 RefSeq Peptide - NP_056530 swissprot - Q9NZ20 Ensembl - ENSG00000100078

See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
CU459012.1	ENSDARG00000098989	Danio rerio
zgc:123275	ENSDARG00000008948	Danio rerio
	ENSGALG00000030512	Gallus gallus
Pla2g3	ENSMUSG00000034579	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
PROCA1 / Q8NCQ7 / protein interacting with cyclin A1	ENSG00000167525	11

Protein motifs (from Interpro)

Interpro ID	Name
IPR016090	Phospholipase A2 domain
IPR033113	Phospholipase A2, histidine active site
IPR036444	Phospholipase A2 domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001675	acrosome assembly	IEA
biological_process	GO:0006629	lipid metabolic process	IEA
biological_process	GO:0006644	phospholipid metabolic process	TAS
biological_process	GO:0007288	sperm axoneme assembly	IEA
biological_process	GO:0016042	lipid catabolic process	IEA
biological_process	GO:0019372	lipoxygenase pathway	IEA
biological_process	GO:0030030	cell projection organization	IEA
biological_process	GO:0036148	phosphatidylglycerol acyl-chain remodeling	TAS
biological_process	GO:0036151	phosphatidylcholine acyl-chain remodeling	TAS
biological_process	GO:0036152	phosphatidylethanolamine acyl-chain remodeling	TAS
biological_process	GO:0043303	mast cell degranulation	IEA
biological_process	GO:0046470	phosphatidylcholine metabolic process	IEA
biological_process	GO:0048468	cell development	IEA
biological_process	GO:0050482	arachidonic acid secretion	IEA
biological_process	GO:0060271	cilium assembly	IMP
cellular_component	GO:0005576	extracellular region	TAS
cellular_component	GO:0005615	extracellular space	TAS
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005814	centriole	IEA
cellular_component	GO:0005856	cytoskeleton	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0042629	mast cell granule	IEA
molecular_function	GO:0004623	phospholipase A2 activity	TAS
molecular_function	GO:0016787	hydrolase activity	IEA
molecular_function	GO:0046872	metal ion binding	IEA
molecular_function	GO:0047498	calcium-dependent phospholipase A2 activity	TAS
molecular_function	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)	IEA
molecular_function	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)	IEA

Pathways (from Reactome)

Pathway description

Acyl chain remodelling of PC

Acyl chain remodelling of PE

Acyl chain remodelling of PG

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr