ENSG00000100554


Homo sapiens
transportATP6V1Dmembraneatpaseiontransmembraneciliumcomplexinsulinreceptortransferrinneutrophildegranulationproteinrecyclingvsubunitdsignalingpathwayregulationmacroautophagycellprojectionorganizationassemblylocalizationphagosomeacidificationlysosomalcentrosome

Features
Gene ID: ENSG00000100554
  
Biological name :ATP6V1D
  
Synonyms : ATP6V1D / ATPase H+ transporting V1 subunit D / Q9Y5K8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q23.3
Gene start: 67294371
Gene end: 67360265
  
Corresponding Affymetrix probe sets: 208898_at (Human Genome U133 Plus 2.0 Array)   208899_x_at (Human Genome U133 Plus 2.0 Array)   214923_at (Human Genome U133 Plus 2.0 Array)   235864_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000452029
Ensembl peptide - ENSP00000452492
Ensembl peptide - ENSP00000452192
Ensembl peptide - ENSP00000216442
Ensembl peptide - ENSP00000450834
Ensembl peptide - ENSP00000450841
Ensembl peptide - ENSP00000450885
Ensembl peptide - ENSP00000451031
Ensembl peptide - ENSP00000451167
Ensembl peptide - ENSP00000451422
Ensembl peptide - ENSP00000451564
NCBI entrez gene - 51382     See in Manteia.
OMIM - 609398
RefSeq - NM_015994
RefSeq Peptide - NP_057078
swissprot - G3V341
swissprot - G3V3T8
swissprot - G3V559
swissprot - G3V5S7
swissprot - H0YJ55
swissprot - H0YJH8
swissprot - H0YJS0
swissprot - A0A024R683
swissprot - Q9Y5K8
swissprot - G3V2S6
swissprot - G3V2V6
Ensembl - ENSG00000100554
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atp6v1dENSDARG00000011175Danio rerio
 ATP6V1DENSGALG00000009570Gallus gallus
 P57746ENSMUSG00000021114Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002699  ATPase, V1 complex, subunit D


Gene Ontology (GO)
establishment of localizationcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscatabolic processcellular metabolic processprocess utilizing autophagic mechanismcellular component organizationmacromolecule localizationimmune responsecell activationimmune effector processcellular component biogenesiscellular localizationregulation of biological qualityestablishment of localizationcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscatabolic processcellular metabolic processprocess utilizing autophagic mechanismcellular component organizationmacromolecule localizationimmune responsecell activationimmune effector processcellular component biogenesiscellular localizationregulation of biological qualityestablishment of localizationcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscatabolic processcellular metabolic processprocess utilizing autophagic mechanismcellular component organizationmacromolecule localizationimmune responsecell activationimmune effector processcellular component biogenesiscellular localizationregulation of biological qualityestablishment of localizationcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscatabolic processcellular metabolic processprocess utilizing autophagic mechanismcellular component organizationmacromolecule localizationimmune responsecell activationimmune effector processcellular component biogenesiscellular localizationregulation of biological qualityestablishment of localizationcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscatabolic processcellular metabolic processprocess utilizing autophagic mechanismcellular component organizationmacromolecule localizationimmune responsecell activationimmune effector processcellular component biogenesiscellular localizationregulation of biological qualityestablishment of localizationcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscatabolic processcellular metabolic processprocess utilizing autophagic mechanismcellular component organizationmacromolecule localizationimmune responsecell activationimmune effector processcellular component biogenesiscellular localizationregulation of biological qualityestablishment of localizationcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscatabolic processcellular metabolic processprocess utilizing autophagic mechanismcellular component organizationmacromolecule localizationimmune responsecell activationimmune effector processcellular component biogenesiscellular localizationregulation of biological qualityestablishment of localizationcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscatabolic processcellular metabolic processprocess utilizing autophagic mechanismcellular component organizationmacromolecule localizationimmune responsecell activationimmune effector processcellular component biogenesiscellular localizationregulation of biological qualityestablishment of localizationcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscatabolic processcellular metabolic processprocess utilizing autophagic mechanismcellular component organizationmacromolecule localizationimmune responsecell activationimmune effector processcellular component biogenesiscellular localizationregulation of biological qualityestablishment of localizationcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscatabolic processcellular metabolic processprocess utilizing autophagic mechanismcellular component organizationmacromolecule localizationimmune responsecell activationimmune effector processcellular component biogenesiscellular localizationregulation of biological qualityestablisestablishment of localizationcell comcell communicationresponseresponse to endogenous stimulusresponseresponse to chemicalcellularcellular response to stimuluscatabolicatabolic processcellularcellular metabolic processprocess process utilizing autophagic mechanismcellularcellular component organizationmacromolmacromolecule localizationimmune rimmune responsecell actcell activationimmune eimmune effector processcellularcellular component biogenesiscellularcellular localizationregulatiregulation of biological quality
protein bindingtransmembrane transporter activityhydrolase activityprotein bindingtransmembrane transporter activityhydrolase activityprotein bindingtransmembrane transporter activityhydrolase activityprotein bindingtransmembrane transporter activityhydrolase activityprotein bindingtransmembrane transporter activityhydrolase activityprotein bindingtransmembrane transporter activityhydrolase activityprotein bindingtransmembrane transporter activityhydrolase activityprotein bindingtransmembrane transporter activityhydrolase activityprotein bindingtransmembrane transporter activityhydrolase activityprotein bindingtransmembrane transporter activityhydrolase activityprotein bindingprotein bindingtransmembrane transporter activitytransmembrane transporter activityhydrolase activityhydrolase activity
cellmembraneorganelleprotein-containing complexextracellular regioncellmembraneorganelleprotein-containing complexextracellular regioncellmembraneorganelleprotein-containing complexextracellular regioncellmembraneorganelleprotein-containing complexextracellular regioncellmembraneorganelleprotein-containing complexextracellular regioncellmembraneorganelleprotein-containing complexextracellular regioncellmembraneorganelleprotein-containing complexextracellular regioncellmembraneorganelleprotein-containing complexextracellular regioncellmembraneorganelleprotein-containing complexextracellular regioncellmembraneorganelleprotein-containing complexextracellular regioncellcellmembranemembraneorganelleorganelleprotein-containing complexprotein-containing complexextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0008286 insulin receptor signaling pathway TAS
 biological_processGO:0016241 regulation of macroautophagy NAS
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0033572 transferrin transport TAS
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0061512 protein localization to cilium IMP
 biological_processGO:0090383 phagosome acidification TAS
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005929 cilium IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0033176 proton-transporting V-type ATPase complex IDA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA


Pathways (from Reactome)
Pathway description
ROS, RNS production in phagocytes
Neutrophil degranulation
Insulin receptor recycling
Transferrin endocytosis and recycling
Ion channel transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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