ENSG00000100918


Homo sapiens

Features
Gene ID: ENSG00000100918
  
Biological name :REC8
  
Synonyms : O95072 / REC8 / REC8 meiotic recombination protein
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q12
Gene start: 24171853
Gene end: 24180257
  
Corresponding Affymetrix probe sets: 218599_at (Human Genome U133 Plus 2.0 Array)   229536_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000452701
Ensembl peptide - ENSP00000453763
Ensembl peptide - ENSP00000482439
Ensembl peptide - ENSP00000482546
Ensembl peptide - ENSP00000453506
NCBI entrez gene - 9985     See in Manteia.
OMIM - 608193
RefSeq - XM_017021841
RefSeq - NM_001048205
RefSeq - NM_005132
RefSeq - XM_011537421
RefSeq Peptide - NP_001041670
RefSeq Peptide - NP_005123
swissprot - A0A075B715
swissprot - H0YM87
swissprot - H0YMV7
swissprot - O95072
Ensembl - ENSG00000100918
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rec8aENSDARG00000078329Danio rerio
 rec8bENSDARG00000069260Danio rerio
 Rec8ENSMUSG00000002324Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006909  Rad21/Rec8-like protein, C-terminal, eukaryotic
 IPR006910  Rad21/Rec8-like protein, N-terminal
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination IEA
 biological_processGO:0001556 oocyte maturation IEA
 biological_processGO:0006302 double-strand break repair IBA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0007129 synapsis IEA
 biological_processGO:0007130 synaptonemal complex assembly IEA
 biological_processGO:0007131 reciprocal meiotic recombination TAS
 biological_processGO:0007141 male meiosis I IEA
 biological_processGO:0007283 spermatogenesis TAS
 biological_processGO:0007286 spermatid development IEA
 biological_processGO:0009566 fertilization IEA
 biological_processGO:0051321 meiotic cell cycle TAS
 biological_processGO:0072520 seminiferous tubule development IEA
 cellular_componentGO:0000228 nuclear chromosome IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000778 condensed nuclear chromosome kinetochore IEA
 cellular_componentGO:0000780 condensed nuclear chromosome, centromeric region IEA
 cellular_componentGO:0000793 condensed chromosome IEA
 cellular_componentGO:0000794 condensed nuclear chromosome IEA
 cellular_componentGO:0000795 synaptonemal complex IEA
 cellular_componentGO:0000798 nuclear cohesin complex IBA
 cellular_componentGO:0000800 lateral element IEA
 cellular_componentGO:0001673 male germ cell nucleus IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0030893 meiotic cohesin complex IBA
 cellular_componentGO:0034991 nuclear meiotic cohesin complex IEA
 molecular_functionGO:0003682 chromatin binding IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Meiotic synapsis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr