ENSG00000101452


Homo sapiens

Features
Gene ID: ENSG00000101452
  
Biological name :DHX35
  
Synonyms : DEAH-box helicase 35 / DHX35 / Q9H5Z1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q11.23
Gene start: 38962299
Gene end: 39039723
  
Corresponding Affymetrix probe sets: 1561132_at (Human Genome U133 Plus 2.0 Array)   218579_s_at (Human Genome U133 Plus 2.0 Array)   234728_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000252011
Ensembl peptide - ENSP00000362420
Ensembl peptide - ENSP00000362422
Ensembl peptide - ENSP00000397997
Ensembl peptide - ENSP00000432603
NCBI entrez gene - 60625     See in Manteia.
RefSeq - XM_017028004
RefSeq - NM_001190809
RefSeq - NM_021931
RefSeq - XM_011528972
RefSeq - XM_011528974
RefSeq Peptide - NP_001177738
RefSeq Peptide - NP_068750
swissprot - Q5THQ7
swissprot - Q5THR1
swissprot - Q9H5Z1
swissprot - F2Z2Z2
Ensembl - ENSG00000101452
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DHX35ENSDARG00000063419Danio rerio
 DHX35ENSGALG00000003658Gallus gallus
 Dhx35ENSMUSG00000027655Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DHX8 / Q14562 / DEAH-box helicase 8ENSG0000006759646
DHX16 / O60231 / DEAH-box helicase 16ENSG0000020456045
DHX15 / O43143 / DEAH-box helicase 15ENSG0000010960642
DHX38 / Q92620 / DEAH-box helicase 38ENSG0000014082942
DHX33 / Q9H6R0 / DEAH-box helicase 33ENSG0000000510041
DHX40 / Q8IX18 / DEAH-box helicase 40ENSG0000010840635
DHX34 / Q14147 / DExH-box helicase 34ENSG0000013481531


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR007502  Helicase-associated domain
 IPR011709  Domain of unknown function DUF1605
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IC
 biological_processGO:0006396 RNA processing IBA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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