ENSG00000104415


Homo sapiens

Features
Gene ID: ENSG00000104415
  
Biological name :WISP1
  
Synonyms : O95388 / WISP1 / WNT1 inducible signaling pathway protein 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q24.22
Gene start: 133191039
Gene end: 133231690
  
Corresponding Affymetrix probe sets: 206796_at (Human Genome U133 Plus 2.0 Array)   211312_s_at (Human Genome U133 Plus 2.0 Array)   229802_at (Human Genome U133 Plus 2.0 Array)   235821_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000220856
Ensembl peptide - ENSP00000367093
Ensembl peptide - ENSP00000427744
Ensembl peptide - ENSP00000429185
Ensembl peptide - ENSP00000250160
NCBI entrez gene - 8840     See in Manteia.
OMIM - 603398
RefSeq - NM_001204869
RefSeq - NM_001204870
RefSeq - NM_003882
RefSeq - NM_080838
RefSeq Peptide - NP_001191798
RefSeq Peptide - NP_001191799
RefSeq Peptide - NP_003873
RefSeq Peptide - NP_543028
swissprot - O95388
swissprot - E5RG88
Ensembl - ENSG00000104415
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wisp1aENSDARG00000054331Danio rerio
 wisp1bENSDARG00000076685Danio rerio
 WISP1ENSGALG00000030115Gallus gallus
 Wisp1ENSMUSG00000005124Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WISP3 / O95389 / WNT1 inducible signaling pathway protein 3ENSG0000011276141
CTGF / P29279 / connective tissue growth factorENSG0000011852341
CYR61 / O00622 / cysteine rich angiogenic inducer 61ENSG0000014287136
NOV / P48745 / nephroblastoma overexpressedENSG0000013699935
WISP2 / O76076 / WNT1 inducible signaling pathway protein 2ENSG0000006420525


Protein motifs (from Interpro)
Interpro ID Name
 IPR000867  Insulin-like growth factor-binding protein, IGFBP
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001007  VWFC domain
 IPR006207  Cystine knot, C-terminal
 IPR006208  Glycoprotein hormone subunit beta
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR012395  IGFBP-related, CNN
 IPR017891  Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0007155 cell adhesion IBA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0060548 negative regulation of cell death IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space NAS
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0005178 integrin binding IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005520 insulin-like growth factor binding IEA
 molecular_functionGO:0008201 heparin binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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