ENSG00000106304


Homo sapiens

Features
Gene ID: ENSG00000106304
  
Biological name :SPAM1
  
Synonyms : P38567 / SPAM1 / sperm adhesion molecule 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q31.32
Gene start: 123925237
Gene end: 123971414
  
Corresponding Affymetrix probe sets: 210536_s_at (Human Genome U133 Plus 2.0 Array)   216972_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000402123
Ensembl peptide - ENSP00000391491
Ensembl peptide - ENSP00000417934
Ensembl peptide - ENSP00000223028
Ensembl peptide - ENSP00000345849
Ensembl peptide - ENSP00000386028
NCBI entrez gene - 6677     See in Manteia.
OMIM - 600930
RefSeq - NM_001174045
RefSeq - NM_001174044
RefSeq - NM_001174046
RefSeq - NM_003117
RefSeq - NM_153189
RefSeq Peptide - NP_001167515
RefSeq Peptide - NP_694859
RefSeq Peptide - NP_001167516
RefSeq Peptide - NP_001167517
RefSeq Peptide - NP_003108
swissprot - P38567
swissprot - C9J2X5
swissprot - Q5D1J4
Ensembl - ENSG00000106304
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spam1ENSDARG00000004199Danio rerio
 SPAM1ENSGALG00000008761Gallus gallus
 Hyal5ENSMUSG00000029678Mus musculus
 Spam1ENSMUSG00000029682Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HYAL4 / Q2M3T9 / hyaluronoglucosaminidase 4ENSG0000010630240
HYAL2 / Q12891 / hyaluronoglucosaminidase 2ENSG0000006800133
HYAL1 / Q12794 / hyaluronoglucosaminidase 1ENSG0000011437833
HYAL3 / O43820 / hyaluronoglucosaminidase 3ENSG0000018679231


Protein motifs (from Interpro)
Interpro ID Name
 IPR001439  Hyaluronidase PH20/Hyaluronidase-5
 IPR013785  Aldolase-type TIM barrel
 IPR017853  Glycoside hydrolase superfamily
 IPR018155  Hyaluronidase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process TAS
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007339 binding of sperm to zona pellucida TAS
 biological_processGO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0035036 sperm-egg recognition TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004415 hyalurononglucosaminidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA


Pathways (from Reactome)
Pathway description
Interaction With Cumulus Cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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