ENSG00000108582


Homo sapiens

Features
Gene ID: ENSG00000108582
  
Biological name :CPD
  
Synonyms : carboxypeptidase D / CPD / O75976
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q11.2
Gene start: 30378905
Gene end: 30469989
  
Corresponding Affymetrix probe sets: 201940_at (Human Genome U133 Plus 2.0 Array)   201941_at (Human Genome U133 Plus 2.0 Array)   201942_s_at (Human Genome U133 Plus 2.0 Array)   201943_s_at (Human Genome U133 Plus 2.0 Array)   229600_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464255
Ensembl peptide - ENSP00000444443
Ensembl peptide - ENSP00000225719
Ensembl peptide - ENSP00000466049
Ensembl peptide - ENSP00000463763
NCBI entrez gene - 1362     See in Manteia.
OMIM - 603102
RefSeq - NM_001199775
RefSeq - NM_001304
RefSeq Peptide - NP_001186704
RefSeq Peptide - NP_001295
swissprot - O75976
swissprot - J3QQJ4
swissprot - J3QRJ9
swissprot - K7ELF0
Ensembl - ENSG00000108582
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpdaENSDARG00000055648Danio rerio
 cpdbENSDARG00000053877Danio rerio
 CPDENSGALG00000004295Gallus gallus
 CpdENSMUSG00000020841Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CPXM1 / Q96SM3 / carboxypeptidase X, M14 family member 1ENSG0000008888217
AEBP1 / Q8IUX7 / AE binding protein 1ENSG0000010662417
CPE / P16870 / carboxypeptidase EENSG0000010947217
CPZ / Q66K79 / carboxypeptidase ZENSG0000010962517
CPXM2 / Q8N436 / carboxypeptidase X, M14 family member 2ENSG0000012189817
CPN1 / P15169 / carboxypeptidase N subunit 1ENSG0000012005415
CPM / P14384 / carboxypeptidase MENSG0000013567814


Protein motifs (from Interpro)
Interpro ID Name
 IPR000834  Peptidase M14, carboxypeptidase A
 IPR008969  Carboxypeptidase-like, regulatory domain superfamily
 IPR015567  Peptidase M14B, caboxypeptidase D
 IPR033848  Carboxypeptidase D, carboxypeptidase-like domain 3
 IPR034224  Carboxypeptidase D, carboxypeptidase-like domain 2
 IPR034241  Carboxypeptidase D, carboxypeptidase-like domain 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006518 peptide metabolic process IBA
 biological_processGO:0016485 protein processing IBA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004180 carboxypeptidase activity IEA
 molecular_functionGO:0004181 metallocarboxypeptidase activity IEA
 molecular_functionGO:0004185 serine-type carboxypeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Golgi Associated Vesicle Biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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