Manteia

ENSG00000109452

Homo sapiens

Features

Gene ID:	ENSG00000109452

Biological name :	INPP4B

Synonyms :	inositol polyphosphate-4-phosphatase type II B / INPP4B / O15327

Possible biological names infered from orthology :

Species:	Homo sapiens

Chr. number:	4
Strand:	-1
Band:	q31.21
Gene start:	142023160
Gene end:	142847432

Corresponding Affymetrix probe sets:	205376_at (Human Genome U133 Plus 2.0 Array) 223878_at (Human Genome U133 Plus 2.0 Array) 235046_at (Human Genome U133 Plus 2.0 Array)

Cross references:	Ensembl peptide - ENSP00000423954 Ensembl peptide - ENSP00000424057 Ensembl peptide - ENSP00000486368 Ensembl peptide - ENSP00000427250 Ensembl peptide - ENSP00000426957 Ensembl peptide - ENSP00000426897 Ensembl peptide - ENSP00000426207 Ensembl peptide - ENSP00000425764 Ensembl peptide - ENSP00000425487 Ensembl peptide - ENSP00000424731 Ensembl peptide - ENSP00000262992 Ensembl peptide - ENSP00000420888 Ensembl peptide - ENSP00000421065 Ensembl peptide - ENSP00000422052 Ensembl peptide - ENSP00000422793 Ensembl peptide - ENSP00000423771 NCBI entrez gene - 8821 See in Manteia. OMIM - 607494 RefSeq - NM_003866 RefSeq - XM_017008798 RefSeq - XM_017008797 RefSeq - XM_017008796 RefSeq - XM_017008795 RefSeq - XM_017008794 RefSeq - XM_011532392 RefSeq - XM_011532391 RefSeq - XM_005263325 RefSeq - XM_005263323 RefSeq - NM_001101669 RefSeq - NM_001331040 RefSeq Peptide - NP_001095139 RefSeq Peptide - NP_001317969 RefSeq Peptide - NP_003857 swissprot - E9PG59 swissprot - O15327 swissprot - Q9BS68 swissprot - H0YA10 swissprot - H0Y9Q3 swissprot - D6R9J5 swissprot - D6RDJ7 swissprot - D6RE59 swissprot - D6RJC3 swissprot - E7EQN9 swissprot - E9PHC0 swissprot - E9PCZ3 Ensembl - ENSG00000109452

See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
inpp4b	ENSDARG00000075201	Danio rerio
INPP4B	ENSGALG00000009880	Gallus gallus
Inpp4b	ENSMUSG00000037940	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
INPP4A / Q96PE3 / inositol polyphosphate-4-phosphatase type I A	ENSG00000040933	40

Protein motifs (from Interpro)

Interpro ID	Name
IPR035892	C2 domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006661	phosphatidylinositol biosynthetic process	TAS
biological_process	GO:0007165	signal transduction	TAS
biological_process	GO:0016311	dephosphorylation	IEA
biological_process	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	IEA
biological_process	GO:0043647	inositol phosphate metabolic process	TAS
cellular_component	GO:0005737	cytoplasm	IBA
cellular_component	GO:0005829	cytosol	TAS
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity	TAS
molecular_function	GO:0016787	hydrolase activity	IEA
molecular_function	GO:0017161	inositol-1,3,4-trisphosphate 4-phosphatase activity	TAS
molecular_function	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	IEA
molecular_function	GO:0052828	inositol-3,4-bisphosphate 4-phosphatase activity	TAS

Pathways (from Reactome)

Pathway description

Synthesis of PIPs at the plasma membrane

Synthesis of PIPs at the early endosome membrane

Synthesis of IP2, IP, and Ins in the cytosol

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr