ENSG00000110048


Homo sapiens

Features
Gene ID: ENSG00000110048
  
Biological name :OSBP
  
Synonyms : OSBP / oxysterol binding protein / P22059
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q12.1
Gene start: 59574398
Gene end: 59616144
  
Corresponding Affymetrix probe sets: 1563051_at (Human Genome U133 Plus 2.0 Array)   201799_s_at (Human Genome U133 Plus 2.0 Array)   201800_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000263847
Ensembl peptide - ENSP00000432399
NCBI entrez gene - 5007     See in Manteia.
OMIM - 167040
RefSeq - NM_002556
RefSeq Peptide - NP_002547
swissprot - P22059
swissprot - H0YCV6
Ensembl - ENSG00000110048
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 osbpENSDARG00000004634Danio rerio
 OsbpENSMUSG00000024687Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OSBP2 / Q969R2 / oxysterol binding protein 2ENSG0000018479260
OSBPL3 / Q9H4L5 / oxysterol binding protein like 3ENSG0000007088228
Q9BXW6 / OSBPL1A / oxysterol binding protein like 1AENSG0000014144728
OSBPL7 / Q9BZF2 / oxysterol binding protein like 7ENSG0000000602526
OSBPL6 / Q9BZF3 / oxysterol binding protein like 6ENSG0000007915626
OSBPL2 / Q9H1P3 / oxysterol binding protein like 2ENSG0000013070321


Protein motifs (from Interpro)
Interpro ID Name
 IPR000648  Oxysterol-binding protein
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR018494  Oxysterol-binding protein, conserved site
 IPR037239  Oxysterol-binding protein superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006699 bile acid biosynthetic process TAS
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0015918 sterol transport IDA
 biological_processGO:0044128 positive regulation of growth of symbiont in host IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0030054 cell junction IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008142 oxysterol binding TAS
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015248 sterol transporter activity TAS
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0070273 phosphatidylinositol-4-phosphate binding IDA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis
Synthesis of bile acids and bile salts


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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