ENSG00000112137


Homo sapiens

Features
Gene ID: ENSG00000112137
  
Biological name :PHACTR1
  
Synonyms : PHACTR1 / phosphatase and actin regulator 1 / Q9C0D0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p24.1
Gene start: 12716805
Gene end: 13290484
  
Corresponding Affymetrix probe sets: 213638_at (Human Genome U133 Plus 2.0 Array)   226397_s_at (Human Genome U133 Plus 2.0 Array)   232045_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000412573
Ensembl peptide - ENSP00000368655
Ensembl peptide - ENSP00000384760
Ensembl peptide - ENSP00000329880
Ensembl peptide - ENSP00000368633
Ensembl peptide - ENSP00000368639
Ensembl peptide - ENSP00000368653
NCBI entrez gene - 221692     See in Manteia.
OMIM - 608723
RefSeq - XM_017010469
RefSeq - XM_017010452
RefSeq - XM_017010454
RefSeq - XM_017010455
RefSeq - XM_017010456
RefSeq - XM_017010457
RefSeq - XM_017010458
RefSeq - XM_017010459
RefSeq - XM_017010460
RefSeq - XM_017010461
RefSeq - XM_017010462
RefSeq - XM_017010463
RefSeq - XM_017010464
RefSeq - XM_017010465
RefSeq - XM_017010466
RefSeq - XM_017010467
RefSeq - NM_001242648
RefSeq - NM_001322308
RefSeq - NM_001322309
RefSeq - NM_001322310
RefSeq - NM_001322311
RefSeq - NM_001322312
RefSeq - NM_001322313
RefSeq - NM_001322314
RefSeq - NM_030948
RefSeq - XM_005248934
RefSeq Peptide - NP_001309241
RefSeq Peptide - NP_001229577
RefSeq Peptide - NP_001309237
RefSeq Peptide - NP_001309238
RefSeq Peptide - NP_001309239
RefSeq Peptide - NP_001309240
RefSeq Peptide - NP_001309242
RefSeq Peptide - NP_001309243
RefSeq Peptide - NP_112210
swissprot - Q5R356
swissprot - Q4VY12
swissprot - Q4VY13
swissprot - H0Y7G2
swissprot - Q9C0D0
swissprot - H0Y3U1
Ensembl - ENSG00000112137
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01085887.1ENSDARG00000110206Danio rerio
 phactr1ENSDARG00000023916Danio rerio
 PHACTR1ENSGALG00000012732Gallus gallus
 Q2M3X8ENSMUSG00000054728Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96KR7 / PHACTR3 / phosphatase and actin regulator 3ENSG0000008749541
Q8IZ21 / PHACTR4 / phosphatase and actin regulator 4ENSG0000020413838
O75167 / PHACTR2 / phosphatase and actin regulator 2ENSG0000011241937


Protein motifs (from Interpro)
Interpro ID Name
 IPR004018  RPEL repeat
 IPR029987  Phosphatase and actin regulator 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031032 actomyosin structure organization IMP
 biological_processGO:0031532 actin cytoskeleton reorganization IEA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0043149 stress fiber assembly IMP
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0048870 cell motility IMP
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004864 protein phosphatase inhibitor activity IEA
 molecular_functionGO:0008157 protein phosphatase 1 binding IEA
 molecular_functionGO:0019888 protein phosphatase regulator activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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