ENSG00000113430


Homo sapiens

Features
Gene ID: ENSG00000113430
  
Biological name :IRX4
  
Synonyms : iroquois homeobox 4 / IRX4 / P78413
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: p15.33
Gene start: 1877413
Gene end: 1887236
  
Corresponding Affymetrix probe sets: 220225_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000424235
Ensembl peptide - ENSP00000423161
Ensembl peptide - ENSP00000481396
Ensembl peptide - ENSP00000482393
Ensembl peptide - ENSP00000231357
Ensembl peptide - ENSP00000421772
Ensembl peptide - ENSP00000422462
NCBI entrez gene - 50805     See in Manteia.
OMIM - 606199
RefSeq - NM_001278632
RefSeq - NM_001278633
RefSeq - NM_001278634
RefSeq - NM_001278635
RefSeq - NM_016358
RefSeq Peptide - NP_057442
RefSeq Peptide - NP_001265562
RefSeq Peptide - NP_001265563
RefSeq Peptide - NP_001265564
RefSeq Peptide - NP_001265561
swissprot - P78413
swissprot - D6RC00
swissprot - D6RAS8
Ensembl - ENSG00000113430
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 irx4aENSDARG00000035648Danio rerio
 irx4bENSDARG00000036051Danio rerio
 IRX4ENSGALG00000022896Gallus gallus
 Irx4ENSMUSG00000021604Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IRX6 / P78412 / iroquois homeobox 6ENSG0000015938734
IRX3 / P78415 / iroquois homeobox 3ENSG0000017750830
IRX1 / P78414 / iroquois homeobox 1ENSG0000017054929
IRX2 / Q9BZI1 / iroquois homeobox 2ENSG0000017056128
IRX5 / P78411 / iroquois homeobox 5ENSG0000017684227
MKX / Q8IYA7 / mohawk homeoboxENSG0000015005115


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003893  Iroquois-class homeodomain protein
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007507 heart development TAS
 biological_processGO:0048561 establishment of animal organ orientation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr