ENSG00000114779


Homo sapiens
hydrolaseABHD14Balphabetafold-foldregulationtranscriptionrnapolymeraseii-phosphoadenosine-phosphosulfatemetabolicprocessnucleusnucleoluscytoplasmcytosolextracellularexosomeproteinbindingactivitycytosolicsulfonationsmallmolecules

Features
Gene ID: ENSG00000114779
  
Biological name :ABHD14B
  
Synonyms : ABHD14B / abhydrolase domain containing 14B / Q96IU4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p21.2
Gene start: 51968510
Gene end: 51983409
  
Corresponding Affymetrix probe sets: 224821_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000420065
Ensembl peptide - ENSP00000433388
Ensembl peptide - ENSP00000318248
Ensembl peptide - ENSP00000354841
Ensembl peptide - ENSP00000378455
Ensembl peptide - ENSP00000417564
NCBI entrez gene - 84836     See in Manteia.
RefSeq - NM_001146314
RefSeq - NM_032750
RefSeq Peptide - NP_001139786
RefSeq Peptide - NP_116139
swissprot - V9HW87
swissprot - F8W9U3
swissprot - Q96IU4
swissprot - B4DQI4
Ensembl - ENSG00000114779
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abhd14bENSDARG00000100531Danio rerio
 ABHD14BENSGALG00000038589Gallus gallus
 Abhd14bENSMUSG00000042073Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BUJ0 / ABHD14A / abhydrolase domain containing 14AENSG0000024848742


Protein motifs (from Interpro)
Interpro ID Name
 IPR000073  Alpha/beta hydrolase fold-1
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processsmall molecule metabolic processnitrogen compound metabnitrogen compound metabolic processbiosynthetic processbiosynthetic processcellular metabolic proccellular metabolic processprimary metabolic proceprimary metabolic processorganic substance metaborganic substance metabolic processsmall molecule metabolismall molecule metabolic process
protein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindinghydrolase activityprotein bindingprotein bindinghydrolase activityhydrolase activity
cellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0050427 3"-phosphoadenosine 5"-phosphosulfate metabolic process TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity TAS


Pathways (from Reactome)
Pathway description
Cytosolic sulfonation of small molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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