ENSG00000115808


Homo sapiens

Features
Gene ID: ENSG00000115808
  
Biological name :STRN
  
Synonyms : O43815 / striatin / STRN
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p22.2
Gene start: 36843640
Gene end: 36966472
  
Corresponding Affymetrix probe sets: 1569813_at (Human Genome U133 Plus 2.0 Array)   1569815_x_at (Human Genome U133 Plus 2.0 Array)   205520_at (Human Genome U133 Plus 2.0 Array)   227422_at (Human Genome U133 Plus 2.0 Array)   230734_x_at (Human Genome U133 Plus 2.0 Array)   236388_at (Human Genome U133 Plus 2.0 Array)   236980_at (Human Genome U133 Plus 2.0 Array)   242989_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000263918
Ensembl peptide - ENSP00000368513
NCBI entrez gene - 6801     See in Manteia.
OMIM - 614765
RefSeq - XM_011533073
RefSeq - NM_003162
RefSeq - XM_005264519
RefSeq Peptide - NP_003153
swissprot - O43815
Ensembl - ENSG00000115808
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 strnENSDARG00000100011Danio rerio
 STRNENSGALG00000010580Gallus gallus
 StrnENSMUSG00000024077Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STRN3 / Q13033 / striatin 3ENSG0000019679264
STRN4 / Q9NRL3 / striatin 4ENSG0000009037251
PLRG1 / O43660 / pleiotropic regulator 1ENSG0000017156613


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR013258  Striatin, N-terminal
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007626 locomotory behavior ISS
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0016055 Wnt signaling pathway IMP
 biological_processGO:0016358 dendrite development ISS
 biological_processGO:0070830 bicellular tight junction assembly NAS
 cellular_componentGO:0000159 protein phosphatase type 2A complex IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005923 bicellular tight junction IDA
 cellular_componentGO:0014069 postsynaptic density ISS
 cellular_componentGO:0016020 membrane ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body ISS
 cellular_componentGO:0043197 dendritic spine ISS
 cellular_componentGO:0045211 postsynaptic membrane ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding NAS
 molecular_functionGO:0030331 estrogen receptor binding IPI
 molecular_functionGO:0044877 protein-containing complex binding IDA
 molecular_functionGO:0051721 protein phosphatase 2A binding IDA
 molecular_functionGO:0070016 armadillo repeat domain binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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