ENSG00000116754


Homo sapiens
mrnaSRSF11rnasplicingprocessingnucleusbindingdomainterminationexport-endtranscriptrecognitionmotifserinearginine-richfactorrna-bindingsuperfamilyviaspliceosomepolymeraseiitranscriptionnucleoplasmnuclearspecknucleicacidproteincleavage

Features
Gene ID: ENSG00000116754
  
Biological name :SRSF11
  
Synonyms : Q05519 / serine and arginine rich splicing factor 11 / SRSF11
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p31.1
Gene start: 70205682
Gene end: 70253052
  
Corresponding Affymetrix probe sets: 200685_at (Human Genome U133 Plus 2.0 Array)   200686_s_at (Human Genome U133 Plus 2.0 Array)   213742_at (Human Genome U133 Plus 2.0 Array)   236948_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000474149
Ensembl peptide - ENSP00000378568
Ensembl peptide - ENSP00000474372
Ensembl peptide - ENSP00000359987
Ensembl peptide - ENSP00000359988
Ensembl peptide - ENSP00000359989
NCBI entrez gene - 9295     See in Manteia.
OMIM - 602010
RefSeq - XM_017002834
RefSeq - NM_001190987
RefSeq - NM_001350605
RefSeq - NM_001350606
RefSeq - NM_001350607
RefSeq - NM_001350608
RefSeq - NM_001350609
RefSeq - NM_004768
RefSeq - XM_017002822
RefSeq - XM_017002823
RefSeq - XM_017002824
RefSeq - XM_017002825
RefSeq - XM_017002826
RefSeq - XM_017002827
RefSeq - XM_017002828
RefSeq - XM_017002829
RefSeq - XM_017002830
RefSeq - XM_017002831
RefSeq - XM_017002832
RefSeq - XM_017002833
RefSeq - XM_005271338
RefSeq - XM_005271339
RefSeq - XM_011542427
RefSeq - XM_011542428
RefSeq - XM_011542431
RefSeq - XM_017002811
RefSeq - XM_017002812
RefSeq - XM_017002813
RefSeq - XM_017002814
RefSeq - XM_017002815
RefSeq - XM_017002816
RefSeq - XM_017002817
RefSeq - XM_017002818
RefSeq - XM_017002819
RefSeq - XM_017002820
RefSeq - XM_017002821
RefSeq Peptide - NP_001177916
RefSeq Peptide - NP_001337534
RefSeq Peptide - NP_001337535
RefSeq Peptide - NP_001337536
RefSeq Peptide - NP_001337537
RefSeq Peptide - NP_001337538
RefSeq Peptide - NP_004759
swissprot - Q05519
swissprot - Q5T757
swissprot - Q5T760
swissprot - S4R3C4
swissprot - B4DWT1
Ensembl - ENSG00000116754
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srsf11ENSDARG00000098574Danio rerio
 SRSF11ENSGALG00000011305Gallus gallus
 Srsf11ENSMUSG00000055436Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SREK1 / Q8WXA9 / splicing regulatory glutamic acid and lysine rich protein 1ENSG0000015391448


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR034447  Serine/arginine-rich splicing factor 11
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compounitrogen compound metabolic processcellular metabocellular metabolic processprimary metabolprimary metabolic processorganic substanorganic substance metabolic processbiosynthetic prbiosynthetic processmacromolecule lmacromolecule localizationestablishment oestablishment of localizationcellular localicellular localizationprotein-containprotein-containing complex localization
organic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingprotein bindingorganic cyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingheterocyclic compound bindingprotein bindingprotein binding
cellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006397 mRNA processing TAS
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0031124 mRNA 3"-end processing TAS
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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