ENSG00000118017


Homo sapiens
membraneactivityA4GNTprocessproteino-linkedgolgitransferaseglycosyltransferasedxdsugar-bindingmotifalpha-glycosyltransferasedomainnucleotide-diphospho-sugartransferasescarbohydratemetabolicglycoproteinbiosynthetico-glycanprocessingregulationepithelialcellproliferationapparatusintegralcomponent

Features
Gene ID: ENSG00000118017
  
Biological name :A4GNT
  
Synonyms : A4GNT / alpha-1,4-N-acetylglucosaminyltransferase / Q9UNA3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q22.3
Gene start: 138123718
Gene end: 138132387
  
Corresponding Affymetrix probe sets: 221131_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000236709
NCBI entrez gene - 51146     See in Manteia.
OMIM - 616709
RefSeq - XM_017006544
RefSeq - NM_016161
RefSeq - XM_017006543
RefSeq Peptide - NP_057245
swissprot - Q9UNA3
Ensembl - ENSG00000118017
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A4GNTENSGALG00000006600Gallus gallus
 A4gntENSMUSG00000037953Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A4GALT / Q9NPC4 / alpha 1,4-galactosyltransferase (P blood group)ENSG0000012827431


Protein motifs (from Interpro)
Interpro ID Name
 IPR007577  Glycosyltransferase, DXD sugar-binding motif
 IPR007652  Alpha 1,4-glycosyltransferase domain
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
primary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processglycosylationepithelial cell proliferationprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processglycosylationepithelial cell proliferationprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processglycosylationepithelial cell proliferationprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processglycosylationepithelial cell proliferationprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processglycosylationepithelial cell proliferationprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processglycosylationepithelial cell proliferationprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processglycosylationepithelial cell proliferationprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processglycosylationepithelial cell proliferationprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processglycosylationepithelial cell proliferationprimary metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processglycosylationepithelial cell proliferationprimary metabolic prprimary metabolic processorganic substance meorganic substance metabolic processnitrogen compound menitrogen compound metabolic processbiosynthetic processbiosynthetic processcellular metabolic pcellular metabolic processglycosylationglycosylationepithelial cell prolepithelial cell proliferation
transferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activitytransferase activity
cellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellcellmembranemembraneorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process TAS
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006493 protein O-linked glycosylation IEA
 biological_processGO:0009101 glycoprotein biosynthetic process IDA
 biological_processGO:0016266 O-glycan processing TAS
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane TAS
 molecular_functionGO:0008375 acetylglucosaminyltransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
O-linked glycosylation of mucins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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