ENSG00000118655


Homo sapiens

Features
Gene ID: ENSG00000118655
  
Biological name :DCLRE1B
  
Synonyms : DCLRE1B / DNA cross-link repair 1B / Q9H816
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p13.2
Gene start: 113905141
Gene end: 113914086
  
Corresponding Affymetrix probe sets: 219490_s_at (Human Genome U133 Plus 2.0 Array)   222889_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358576
NCBI entrez gene - 64858     See in Manteia.
OMIM - 609683
RefSeq - NM_022836
RefSeq - NM_001319946
RefSeq Peptide - NP_001306875
RefSeq Peptide - NP_073747
swissprot - Q9H816
Ensembl - ENSG00000118655
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B0V2S2ENSDARG00000068833Danio rerio
 DCLRE1BENSGALG00000028626Gallus gallus
 Q8C7W7ENSMUSG00000027845Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96SD1 / DCLRE1C / DNA cross-link repair 1CENSG0000015245723
Q6PJP8 / DCLRE1A / DNA cross-link repair 1AENSG0000019892410


Protein motifs (from Interpro)
Interpro ID Name
 IPR011084  DNA repair metallo-beta-lactamase
 IPR036866  Ribonuclease Z/Hydroxyacylglutathione hydrolase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000075 cell cycle checkpoint IMP
 biological_processGO:0000723 telomere maintenance IMP
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006303 double-strand break repair via nonhomologous end joining IBA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0010833 telomere maintenance via telomere lengthening IMP
 biological_processGO:0016233 telomere capping IMP
 biological_processGO:0031627 telomeric loop formation IEA
 biological_processGO:0031848 protection from non-homologous end joining at telomere IEA
 biological_processGO:0031860 telomeric 3" overhang formation IEA
 biological_processGO:0036297 interstrand cross-link repair IMP
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0000781 chromosome, telomeric region IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016604 nuclear body IDA
 molecular_functionGO:0003684 damaged DNA binding IBA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008409 5"-3" exonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0035312 5"-3" exodeoxyribonuclease activity IBA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0044877 protein-containing complex binding IPI


Pathways (from Reactome)
Pathway description
Fanconi Anemia Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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