ENSG00000124564


Homo sapiens

Features
Gene ID: ENSG00000124564
  
Biological name :SLC17A3
  
Synonyms : O00476 / SLC17A3 / solute carrier family 17 member 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p22.2
Gene start: 25833066
Gene end: 25882286
  
Corresponding Affymetrix probe sets: 207298_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000415622
Ensembl peptide - ENSP00000424729
Ensembl peptide - ENSP00000424027
Ensembl peptide - ENSP00000421855
Ensembl peptide - ENSP00000353873
Ensembl peptide - ENSP00000355307
Ensembl peptide - ENSP00000380250
NCBI entrez gene - 10786     See in Manteia.
OMIM - 611034
RefSeq - NM_001098486
RefSeq - NM_006632
RefSeq Peptide - NP_001091956
RefSeq Peptide - NP_006623
swissprot - O00476
swissprot - A0A024QZX7
swissprot - H0Y8R7
swissprot - H0Y9F7
swissprot - E9PBQ8
Ensembl - ENSG00000124564
  
Related genetic diseases (OMIM): 612671 - [Uric acid concentration, serum, QTL4], 612671
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC17A3ENSDARG00000086739Danio rerio
 Slc17a3ENSMUSG00000036083Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O00624 / SLC17A2 / solute carrier family 17 member 2ENSG0000011233753
Q9Y2C5 / SLC17A4 / solute carrier family 17 member 4ENSG0000014603952
Q14916 / SLC17A1 / solute carrier family 17 member 1ENSG0000012456845
Q9NRA2 / SLC17A5 / solute carrier family 17 member 5ENSG0000011989932
Q9P2U8 / SLC17A6 / solute carrier family 17 member 6ENSG0000009166430
Q9P2U7 / SLC17A7 / solute carrier family 17 member 7ENSG0000010488829
Q8NDX2 / SLC17A8 / solute carrier family 17 member 8ENSG0000017952029
Q9BYT1 / SLC17A9 / solute carrier family 17 member 9ENSG0000010119421


Protein motifs (from Interpro)
Interpro ID Name
 IPR011701  Major facilitator superfamily
 IPR017373  Sodium-dependent phosphate transport protein 4 , predicted
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport ISS
 biological_processGO:0006817 phosphate ion transport ISS
 biological_processGO:0006855 drug transmembrane transport IEA
 biological_processGO:0015711 organic anion transport IDA
 biological_processGO:0015747 urate transport IDA
 biological_processGO:0015760 glucose-6-phosphate transport TAS
 biological_processGO:0015893 drug transport IDA
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0035725 sodium ion transmembrane transport IBA
 biological_processGO:0046415 urate metabolic process IMP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:1901998 toxin transport IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0031526 brush border membrane ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0005436 sodium:phosphate symporter activity TAS
 molecular_functionGO:0008308 voltage-gated anion channel activity IDA
 molecular_functionGO:0008514 organic anion transmembrane transporter activity IDA
 molecular_functionGO:0015143 urate transmembrane transporter activity TAS
 molecular_functionGO:0015238 drug transmembrane transporter activity IDA
 molecular_functionGO:0015293 symporter activity IEA
 molecular_functionGO:0015562 efflux transmembrane transporter activity IDA
 molecular_functionGO:0019534 toxin transmembrane transporter activity IDA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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