ENSG00000126062


Homo sapiens
golgiTMEM115proteintransportmembraneervesicle-mediatedbindingtransmembranedufeukaryoticrhomboid-likesuperfamilyglycosylationretrograderegulationcellproliferationnucleusapparatusintegralcomponentcomplexcisternamolecularfunctionidenticalcopi-mediatedanterograde

Features
Gene ID: ENSG00000126062
  
Biological name :TMEM115
  
Synonyms : Q12893 / TMEM115 / transmembrane protein 115
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p21.31
Gene start: 50354749
Gene end: 50359610
  
Corresponding Affymetrix probe sets: 216267_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000266025
NCBI entrez gene - 11070     See in Manteia.
OMIM - 607069
RefSeq - NM_007024
RefSeq Peptide - NP_008955
swissprot - A0A024R2Y2
swissprot - Q12893
Ensembl - ENSG00000126062
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmem115ENSDARG00000055763Danio rerio
 TMEM115ENSGALG00000026965Gallus gallus
 Q9WUH1ENSMUSG00000010045Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013861  Transmembrane protein DUF1751, eukaryotic
 IPR035952  Rhomboid-like superfamily


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationestablishment of localizationcellular localizationmacromolecule localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationestablishment of localizationcellular localizationmacromolecule localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationestablishment of localizationcellular localizationmacromolecule localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationestablishment of localizationcellular localizationmacromolecule localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationestablishment of localizationcellular localizationmacromolecule localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationestablishment of localizationcellular localizationmacromolecule localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationestablishment of localizationcellular localizationmacromolecule localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationestablishment of localizationcellular localizationmacromolecule localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationestablishment of localizationcellular localizationmacromolecule localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processglycosylationestablishment of localizationcellular localizationmacromolecule localizationnitrogen compounitrogen compound metabolic processbiosynthetic prbiosynthetic processcellular metabocellular metabolic processprimary metabolprimary metabolic processorganic substanorganic substance metabolic processglycosylationglycosylationestablishment oestablishment of localizationcellular localicellular localizationmacromolecule lmacromolecule localization
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellmembraneorganelleprotein-containing complexcellcellmembranemembraneorganelleorganelleprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IMP
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport TAS
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IMP
 biological_processGO:0008285 negative regulation of cell proliferation NAS
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0017119 Golgi transport complex IDA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042802 identical protein binding IDA


Pathways (from Reactome)
Pathway description
COPI-mediated anterograde transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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