ENSG00000126804


Homo sapiens

Features
Gene ID: ENSG00000126804
  
Biological name :ZBTB1
  
Synonyms : Q9Y2K1 / ZBTB1 / zinc finger and BTB domain containing 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q23.3
Gene start: 64503712
Gene end: 64533690
  
Corresponding Affymetrix probe sets: 1557036_at (Human Genome U133 Plus 2.0 Array)   205092_x_at (Human Genome U133 Plus 2.0 Array)   213376_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000450689
Ensembl peptide - ENSP00000451332
Ensembl peptide - ENSP00000451584
Ensembl peptide - ENSP00000351587
Ensembl peptide - ENSP00000451000
NCBI entrez gene - 22890     See in Manteia.
OMIM - 616578
RefSeq - XM_017021095
RefSeq - NM_001123329
RefSeq - NM_014950
RefSeq - XM_005267410
RefSeq - XM_011536566
RefSeq - XM_011536568
RefSeq - XM_017021094
RefSeq Peptide - NP_001116801
RefSeq Peptide - NP_055765
swissprot - G3V3N0
swissprot - G3V447
swissprot - Q9Y2K1
swissprot - G3V2I8
Ensembl - ENSG00000126804
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zbtb1ENSDARG00000023040Danio rerio
 ZBTB1ENSGALG00000011718Gallus gallus
 Zbtb1ENSMUSG00000033454Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ZBTB2 / Q8N680 / zinc finger and BTB domain containing 2ENSG000001814729
P24278 / ZBTB25 / zinc finger and BTB domain containing 25ENSG000000897757


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR026939  At2g23090-like
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002711 positive regulation of T cell mediated immunity ISS
 biological_processGO:0006281 DNA repair IMP
 biological_processGO:0006338 chromatin remodeling IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0019985 translesion synthesis IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030183 B cell differentiation IEA
 biological_processGO:0032825 positive regulation of natural killer cell differentiation ISS
 biological_processGO:0033077 T cell differentiation in thymus IEA
 biological_processGO:0034644 cellular response to UV IMP
 biological_processGO:0042789 mRNA transcription by RNA polymerase II IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045582 positive regulation of T cell differentiation ISS
 biological_processGO:0048538 thymus development ISS
 biological_processGO:0051260 protein homooligomerization IDA
 biological_processGO:2000176 positive regulation of pro-T cell differentiation ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0031965 nuclear membrane IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IDA
 molecular_functionGO:0070530 K63-linked polyubiquitin modification-dependent protein binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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