ENSG00000126821


Homo sapiens

Features
Gene ID: ENSG00000126821
  
Biological name :SGPP1
  
Synonyms : Q9BX95 / SGPP1 / sphingosine-1-phosphate phosphatase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q23.2
Gene start: 63684214
Gene end: 63728039
  
Corresponding Affymetrix probe sets: 221268_s_at (Human Genome U133 Plus 2.0 Array)   223391_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000247225
NCBI entrez gene - 81537     See in Manteia.
OMIM - 612826
RefSeq - NM_030791
RefSeq - XM_017021678
RefSeq Peptide - NP_110418
swissprot - Q9BX95
Ensembl - ENSG00000126821
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sgpp1ENSDARG00000060534Danio rerio
 si:ch211-212g7.6ENSDARG00000079369Danio rerio
 SGPP1ENSGALG00000041183Gallus gallus
 Sgpp1ENSMUSG00000021054Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SGPP2 / Q8IWX5 / sphingosine-1-phosphate phosphatase 2ENSG0000016308234


Protein motifs (from Interpro)
Interpro ID Name
 IPR000326  Phosphatidic acid phosphatase type 2/haloperoxidase
 IPR036938  Phosphatidic acid phosphatase type 2/haloperoxidase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0006668 sphinganine-1-phosphate metabolic process IEA
 biological_processGO:0006670 sphingosine metabolic process IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0030148 sphingolipid biosynthetic process TAS
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IEA
 biological_processGO:0097193 intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042392 sphingosine-1-phosphate phosphatase activity IEA
 molecular_functionGO:0070780 dihydrosphingosine-1-phosphate phosphatase activity TAS


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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