ENSG00000134780


Homo sapiens

Features
Gene ID: ENSG00000134780
  
Biological name :DAGLA
  
Synonyms : DAGLA / diacylglycerol lipase alpha / Q9Y4D2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q12.2
Gene start: 61680433
Gene end: 61747001
  
Corresponding Affymetrix probe sets: 214128_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000440264
Ensembl peptide - ENSP00000257215
NCBI entrez gene - 747     See in Manteia.
OMIM - 614015
RefSeq - XM_017018240
RefSeq - NM_006133
RefSeq - XM_017018238
RefSeq - XM_017018239
RefSeq Peptide - NP_006124
swissprot - Q9Y4D2
swissprot - F5GY58
swissprot - A0A024R517
Ensembl - ENSG00000134780
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 daglaENSDARG00000062956Danio rerio
 DAGLAENSGALG00000036492Gallus gallus
 DaglaENSMUSG00000035735Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DAGLB / Q8NCG7 / diacylglycerol lipase betaENSG0000016453522


Protein motifs (from Interpro)
Interpro ID Name
 IPR002921  Fungal lipase-like domain
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007216 G-protein coupled glutamate receptor signaling pathway IEA
 biological_processGO:0007405 neuroblast proliferation IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0019369 arachidonic acid metabolic process IDA
 biological_processGO:0022008 neurogenesis IEA
 biological_processGO:0042136 neurotransmitter biosynthetic process IDA
 biological_processGO:0046340 diacylglycerol catabolic process IDA
 biological_processGO:0071926 endocannabinoid signaling pathway IEA
 biological_processGO:0098921 retrograde trans-synaptic signaling by endocannabinoid IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043196 varicosity IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047372 acylglycerol lipase activity TAS


Pathways (from Reactome)
Pathway description
Arachidonate production from DAG


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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