ENSG00000134996


Homo sapiens
domainOSTF1shankyrinrepeat-containingsuperfamilyneutrophildegranulationextracellulargranulelumenbindingrepeat-likeossificationsignaltransductionregionintracellularcytoplasmsecretoryexosomeficolin--richprotein

Features
Gene ID: ENSG00000134996
  
Biological name :OSTF1
  
Synonyms : osteoclast stimulating factor 1 / OSTF1 / Q92882
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q21.13
Gene start: 75088543
Gene end: 75147265
  
Corresponding Affymetrix probe sets: 204479_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000340836
NCBI entrez gene - 26578     See in Manteia.
OMIM - 610180
RefSeq - XM_017014622
RefSeq - NM_012383
RefSeq - XM_011518524
RefSeq - XM_011518525
RefSeq - XM_006717053
RefSeq - XM_006717055
RefSeq Peptide - NP_036515
swissprot - Q92882
Ensembl - ENSG00000134996
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ostf1ENSDARG00000091555Danio rerio
 OSTF1ENSGALG00000017447Gallus gallus
 Ostf1ENSMUSG00000024725Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR036028  SH3-like domain superfamily
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
ossificationcell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processossificationcell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processossificationcell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processossificationcell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processossificationcell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processossificationcell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processossificationcell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processossificationcell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processossificationcell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processossificationcell communicationcellular response to stimulusimmune responseestablishment of localizationcell activationimmune effector processossificationossificationcell communicationcell communicationcellular response tocellular response to stimulusimmune responseimmune responseestablishment of locestablishment of localizationcell activationcell activationimmune effector procimmune effector process
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
extracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regioncellorganellemembrane-enclosed lumenextracellular regionextracellular regioncellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0001503 ossification TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005622 intracellular TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017124 SH3 domain binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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