ENSG00000135390


Homo sapiens

Features
Gene ID: ENSG00000135390
  
Biological name :ATP5MC2
  
Synonyms : ATP5MC2 / ATP synthase membrane subunit c locus 2 / Q06055
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.13
Gene start: 53632726
Gene end: 53677408
  
Corresponding Affymetrix probe sets: 207552_at (Human Genome U133 Plus 2.0 Array)   208764_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473535
Ensembl peptide - ENSP00000447643
Ensembl peptide - ENSP00000448801
Ensembl peptide - ENSP00000340315
Ensembl peptide - ENSP00000377878
Ensembl peptide - ENSP00000447317
NCBI entrez gene - 517     See in Manteia.
OMIM - 603193
RefSeq - XM_017019462
RefSeq - NM_001002031
RefSeq - NM_005176
RefSeq - XM_017019460
RefSeq - XM_017019461
RefSeq Peptide - NP_001002031
RefSeq Peptide - NP_005167
swissprot - Q06055
swissprot - F8W041
Ensembl - ENSG00000135390
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATP5MC2ENSGALG00000030086Gallus gallus
 Atp5g2ENSMUSG00000062683Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P48201 / ATP5MC3 / ATP synthase membrane subunit c locus 3ENSG0000015451853
P05496 / ATP5MC1 / ATP synthase membrane subunit c locus 1ENSG0000015919949


Protein motifs (from Interpro)
Interpro ID Name
 IPR000454  ATP synthase, F0 complex, subunit C
 IPR002379  V-ATPase proteolipid subunit C-like domain
 IPR020537  ATP synthase, F0 complex, subunit C, DCCD-binding site
 IPR035921  F/V-ATP synthase subunit C superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006754 ATP biosynthetic process TAS
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0015986 ATP synthesis coupled proton transport IBA
 biological_processGO:0015991 ATP hydrolysis coupled proton transport IEA
 biological_processGO:0042407 cristae formation TAS
 biological_processGO:0042776 mitochondrial ATP synthesis coupled proton transport TAS
 cellular_componentGO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) IBA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0005753 mitochondrial proton-transporting ATP synthase complex TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain IEA
 cellular_componentGO:0045263 proton-transporting ATP synthase complex, coupling factor F(o) IEA
 molecular_functionGO:0005215 transporter activity NAS
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015078 proton transmembrane transporter activity IEA
 molecular_functionGO:0046933 proton-transporting ATP synthase activity, rotational mechanism IBA


Pathways (from Reactome)
Pathway description
Formation of ATP by chemiosmotic coupling
Cristae formation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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