ENSG00000135577


Homo sapiens

Features
Gene ID: ENSG00000135577
  
Biological name :NMBR
  
Synonyms : neuromedin B receptor / NMBR / P28336
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q24.1
Gene start: 142058330
Gene end: 142088799
  
Corresponding Affymetrix probe sets: 207333_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000258042
NCBI entrez gene - 4829     See in Manteia.
OMIM - 162341
RefSeq - NM_002511
RefSeq - XM_017010902
RefSeq - NM_001324307
RefSeq - NM_001324308
RefSeq Peptide - NP_001311237
RefSeq Peptide - NP_002502
RefSeq Peptide - NP_001311236
swissprot - P28336
Ensembl - ENSG00000135577
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nmbrENSDARG00000054152Danio rerio
 NMBRENSGALG00000013813Gallus gallus
 NmbrENSMUSG00000019865Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRPR / P30550 / gastrin releasing peptide receptorENSG0000012601054
BRS3 / P32247 / bombesin receptor subtype 3ENSG0000010223947
EDNRB / P24530 / endothelin receptor type BENSG0000013616030
EDNRA / P25101 / endothelin receptor type AENSG0000015161729
GPR37 / O15354 / G protein-coupled receptor 37ENSG0000017077524
O60883 / GPR37L1 / G protein-coupled receptor 37 like 1ENSG0000017007520


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001556  Bombesin receptor-like
 IPR001642  Neuromedin B receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway TAS
 biological_processGO:0031989 bombesin receptor signaling pathway IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004946 bombesin receptor activity TAS
 molecular_functionGO:0008528 G-protein coupled peptide receptor activity IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000134443 GRP / P07492 / gastrin releasing peptide  / complex / reaction
 ENSG00000197696 NMB / P08949 / neuromedin B  / complex / reaction






 

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