ENSG00000135624


Homo sapiens
proteinCCT7foldingbindingccttricregulationchaperonintcp-localizationbodycpnt-complexcomplexgroel-likedomainsuperfamilyzonapellucidatelomeretelomerasecajalconservedsitefamilyetasubunitchaperonetaillesspolypeptideapical

Features
Gene ID: ENSG00000135624
  
Biological name :CCT7
  
Synonyms : CCT7 / chaperonin containing TCP1 subunit 7 / Q99832
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p13.2
Gene start: 73233420
Gene end: 73253021
  
Corresponding Affymetrix probe sets: 200812_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000442058
Ensembl peptide - ENSP00000437824
Ensembl peptide - ENSP00000487267
Ensembl peptide - ENSP00000258091
Ensembl peptide - ENSP00000381456
Ensembl peptide - ENSP00000386978
Ensembl peptide - ENSP00000412996
NCBI entrez gene - 10574     See in Manteia.
OMIM - 605140
RefSeq - XM_011532479
RefSeq - NM_001009570
RefSeq - NM_001166284
RefSeq - NM_001166285
RefSeq - NM_006429
RefSeq - XM_011532478
RefSeq Peptide - NP_001159756
RefSeq Peptide - NP_001159757
RefSeq Peptide - NP_006420
RefSeq Peptide - NP_001009570
swissprot - Q99832
swissprot - F8WAM2
swissprot - F8WBP8
swissprot - A0A0D9SG95
Ensembl - ENSG00000135624
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cct7ENSDARG00000007385Danio rerio
 CCT7ENSGALG00000016088Gallus gallus
 Cct7ENSMUSG00000030007Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001844  Chaperonin Cpn60
 IPR002194  Chaperonin TCP-1, conserved site
 IPR002423  Chaperonin Cpn60/TCP-1 family
 IPR012720  T-complex protein 1, eta subunit
 IPR017998  Chaperone tailless complex polypeptide 1 (TCP-1)
 IPR027409  GroEL-like apical domain superfamily
 IPR027413  GroEL-like equatorial domain superfamily


Gene Ontology (GO)
protein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processestablishment of localizationmacromolecule localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processestablishment of localizationmacromolecule localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processestablishment of localizationmacromolecule localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processestablishment of localizationmacromolecule localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processestablishment of localizationmacromolecule localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processestablishment of localizationmacromolecule localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processestablishment of localizationmacromolecule localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processestablishment of localizationmacromolecule localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processestablishment of localizationmacromolecule localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processestablishment of localizationmacromolecule localizationcellular localizationprotein folprotein foldingcell recogncell recognitionnitrogen conitrogen compound metabolic processbiosynthetibiosynthetic processcellular cocellular component organizationcellular mecellular metabolic processprimary metprimary metabolic processregulation regulation of biological qualityorganic suborganic substance metabolic processestablishmeestablishment of localizationmacromolecumacromolecule localizationcellular locellular localization
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compoorganic cyclic compound bindingheterocyclic compounheterocyclic compound bindingsmall molecule bindismall molecule bindingprotein bindingprotein bindingion bindingion bindingcarbohydrate derivatcarbohydrate derivative bindingdrug bindingdrug binding
protein-containing complexcellorganellesupramolecular complexextracellular regionprotein-containing complexcellorganellesupramolecular complexextracellular regionprotein-containing complexcellorganellesupramolecular complexextracellular regionprotein-containing complexcellorganellesupramolecular complexextracellular regionprotein-containing complexcellorganellesupramolecular complexextracellular regionprotein-containing complexcellorganellesupramolecular complexextracellular regionprotein-containing complexcellorganellesupramolecular complexextracellular regionprotein-containing complexcellorganellesupramolecular complexextracellular regionprotein-containing complexcellorganellesupramolecular complexextracellular regionprotein-containing complexcellorganellesupramolecular complexextracellular regionprotein-containing complexprotein-containing complexcellcellorganelleorganellesupramolecular complexsupramolecular complexextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006458 "de novo" protein folding IBA
 biological_processGO:0007339 binding of sperm to zona pellucida IEA
 biological_processGO:0032212 positive regulation of telomere maintenance via telomerase IMP
 biological_processGO:0042026 protein refolding IEA
 biological_processGO:0050821 protein stabilization IMP
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 biological_processGO:1901998 toxin transport IEA
 biological_processGO:1904851 positive regulation of establishment of protein localization to telomere IMP
 biological_processGO:1904871 positive regulation of protein localization to Cajal body IMP
 biological_processGO:1904874 positive regulation of telomerase RNA localization to Cajal body IMP
 cellular_componentGO:0002199 zona pellucida receptor complex IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005832 chaperonin-containing T-complex TAS
 cellular_componentGO:0005874 microtubule IDA
 cellular_componentGO:0044297 cell body IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IBA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Folding of actin by CCT/TriC
Association of TriC/CCT with target proteins during biosynthesis
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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