ENSG00000136451


Homo sapiens

Features
Gene ID: ENSG00000136451
  
Biological name :VEZF1
  
Synonyms : Q14119 / vascular endothelial zinc finger 1 / VEZF1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q22
Gene start: 57971547
Gene end: 57988259
  
Corresponding Affymetrix probe sets: 202171_at (Human Genome U133 Plus 2.0 Array)   202172_at (Human Genome U133 Plus 2.0 Array)   202173_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000258963
Ensembl peptide - ENSP00000462337
Ensembl peptide - ENSP00000463631
Ensembl peptide - ENSP00000464687
NCBI entrez gene - 7716     See in Manteia.
OMIM - 606747
RefSeq - XM_017025018
RefSeq - NM_007146
RefSeq - XM_005257643
RefSeq - XM_005257644
RefSeq - XM_017025017
RefSeq Peptide - NP_009077
RefSeq Peptide - NP_001317322
swissprot - Q14119
swissprot - J3QSH4
swissprot - J9JIC7
swissprot - J3QLN5
Ensembl - ENSG00000136451
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vezf1aENSDARG00000008247Danio rerio
 vezf1bENSDARG00000061030Danio rerio
 VEZF1ENSGALG00000005530Gallus gallus
 Vezf1ENSMUSG00000018377Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAZ / P56270 / MYC associated zinc finger proteinENSG0000010349530
PATZ1 / Q9HBE1 / POZ/BTB and AT hook containing zinc finger 1ENSG0000010010527


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR035500  Nuclear hormone receptor-like domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001885 endothelial cell development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006968 cellular defense response TAS
 biological_processGO:0045603 positive regulation of endothelial cell differentiation IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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