ENSG00000137628


Homo sapiens

Features
Gene ID: ENSG00000137628
  
Biological name :DDX60
  
Synonyms : DDX60 / DExD/H-box helicase 60 / Q8IY21
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q32.3
Gene start: 168216293
Gene end: 168318807
  
Corresponding Affymetrix probe sets: 218986_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000423678
Ensembl peptide - ENSP00000377344
Ensembl peptide - ENSP00000422669
Ensembl peptide - ENSP00000423647
NCBI entrez gene - 55601     See in Manteia.
OMIM - 613974
RefSeq - XM_011532104
RefSeq - NM_017631
RefSeq - XM_011532103
RefSeq Peptide - NP_060101
swissprot - D6R944
swissprot - Q8IY21
swissprot - H0Y8Z7
swissprot - H0Y9B2
Ensembl - ENSG00000137628
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000038140Gallus gallus
 ENSGALG00000009639Gallus gallus
 Ddx60ENSMUSG00000037921Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DDX60L / Q5H9U9 / DExD/H-box 60 likeENSG0000018138165
Q15477 / SKIV2L / Ski2 like RNA helicaseENSG0000020435113
MTREX / P42285 / Mtr4 exosome RNA helicaseENSG0000003912312


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0009615 response to virus IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:1900245 positive regulation of MDA-5 signaling pathway IMP
 biological_processGO:1900246 positive regulation of RIG-I signaling pathway IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0045111 intermediate filament cytoskeleton IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IDA
 molecular_functionGO:0003727 single-stranded RNA binding IDA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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