ENSG00000138594


Homo sapiens

Features
Gene ID: ENSG00000138594
  
Biological name :TMOD3
  
Synonyms : Q9NYL9 / TMOD3 / tropomodulin 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q21.2
Gene start: 51829628
Gene end: 51947295
  
Corresponding Affymetrix probe sets: 220800_s_at (Human Genome U133 Plus 2.0 Array)   223077_at (Human Genome U133 Plus 2.0 Array)   223078_s_at (Human Genome U133 Plus 2.0 Array)   242316_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000308753
Ensembl peptide - ENSP00000452939
Ensembl peptide - ENSP00000454040
Ensembl peptide - ENSP00000454161
NCBI entrez gene - 29766     See in Manteia.
OMIM - 605112
RefSeq - XM_017022088
RefSeq - NM_014547
RefSeq - XM_017022087
RefSeq Peptide - NP_055362
swissprot - H0YKU1
swissprot - Q9NYL9
swissprot - H0YNJ8
swissprot - H0YNU8
Ensembl - ENSG00000138594
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmod2ENSDARG00000002571Danio rerio
 TMOD3ENSGALG00000004710Gallus gallus
 Tmod3ENSMUSG00000058587Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TMOD2 / Q9NZR1 / tropomodulin 2ENSG0000012887276
TMOD1 / P28289 / tropomodulin 1ENSG0000013684261
TMOD4 / Q9NZQ9 / tropomodulin 4ENSG0000016315754
LMOD2 / Q6P5Q4 / leiomodin 2ENSG0000017080739
LMOD1 / P29536 / leiomodin 1ENSG0000016343137
LMOD3 / Q0VAK6 / leiomodin 3ENSG0000016338034


Protein motifs (from Interpro)
Interpro ID Name
 IPR004934  Tropomodulin
 IPR030133  Tropomodulin-3
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction IBA
 biological_processGO:0007015 actin filament organization IBA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0030239 myofibril assembly IBA
 biological_processGO:0048821 erythrocyte development IEA
 biological_processGO:0051694 pointed-end actin filament capping IEA
 biological_processGO:0098609 cell-cell adhesion IEA
 biological_processGO:1901992 positive regulation of mitotic cell cycle phase transition IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005865 striated muscle thin filament IEA
 cellular_componentGO:0005913 cell-cell adherens junction IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005523 tropomyosin binding IEA
 molecular_functionGO:0098641 cadherin binding involved in cell-cell adhesion IDA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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