ENSG00000140254


Homo sapiens
regulationmembraneDUOXA1metabolicprocessdualoxidasematurationfactorproteintransporthydrogenperoxideneurondifferentiationinflammatoryresponsereactiveoxygenspeciesthyroidhormonegenerationendoplasmicreticulumplasmaintegralcomponent

Features
Gene ID: ENSG00000140254
  
Biological name :DUOXA1
  
Synonyms : dual oxidase maturation factor 1 / DUOXA1 / Q1HG43
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q21.1
Gene start: 45117367
Gene end: 45129938
  
Corresponding Affymetrix probe sets: 1554648_a_at (Human Genome U133 Plus 2.0 Array)   1555404_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453836
Ensembl peptide - ENSP00000453809
Ensembl peptide - ENSP00000454019
Ensembl peptide - ENSP00000480154
Ensembl peptide - ENSP00000454117
Ensembl peptide - ENSP00000454084
Ensembl peptide - ENSP00000267803
Ensembl peptide - ENSP00000415512
Ensembl peptide - ENSP00000452782
Ensembl peptide - ENSP00000452795
Ensembl peptide - ENSP00000453217
Ensembl peptide - ENSP00000453295
Ensembl peptide - ENSP00000453569
Ensembl peptide - ENSP00000453614
NCBI entrez gene - 90527     See in Manteia.
OMIM - 612771
RefSeq - XM_011522186
RefSeq - NM_001276266
RefSeq - NM_001276267
RefSeq - NM_001276268
RefSeq - NM_144565
RefSeq - XM_006720743
RefSeq - XM_006720745
RefSeq - XM_006720746
RefSeq - XM_006720747
RefSeq - XM_006720749
RefSeq - XM_006720751
RefSeq - XM_006720752
RefSeq - XM_006720754
RefSeq - XM_006720755
RefSeq - XM_011522181
RefSeq - XM_011522182
RefSeq - XM_011522183
RefSeq - XM_011522184
RefSeq - XM_011522185
RefSeq - NM_001276264
RefSeq - NM_001276265
RefSeq Peptide - NP_001263197
RefSeq Peptide - NP_653166
RefSeq Peptide - NP_001263195
RefSeq Peptide - NP_001263196
RefSeq Peptide - NP_001263193
RefSeq Peptide - NP_001263194
swissprot - H0YLQ4
swissprot - H0YMH9
swissprot - H0YMZ8
swissprot - B5M0C0
swissprot - Q1HG43
swissprot - A8K9Q6
swissprot - H0YNR1
swissprot - B5M0B8
swissprot - B5M0B7
swissprot - H0YKF3
swissprot - H0YKG3
swissprot - H0YLI1
Ensembl - ENSG00000140254
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 duox2ENSDARG00000078962Danio rerio
 ENSGALG00000036511Gallus gallus
 ENSGALG00000035246Gallus gallus
 Duoxa1ENSMUSG00000027224Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DUOXA2 / Q1HG44 / dual oxidase maturation factor 2ENSG0000014027435


Protein motifs (from Interpro)
Interpro ID Name
 IPR018469  Dual oxidase maturation factor


Gene Ontology (GO)
macromolecule localizationestablishment of localizationcellular metabolic processanatomical structure developmentcellular developmental processresponse to stressresponse to external stimulusnitrogen compound metabolic processregulation of biological qualityorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processanatomical structure developmentcellular developmental processresponse to stressresponse to external stimulusnitrogen compound metabolic processregulation of biological qualityorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processanatomical structure developmentcellular developmental processresponse to stressresponse to external stimulusnitrogen compound metabolic processregulation of biological qualityorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processanatomical structure developmentcellular developmental processresponse to stressresponse to external stimulusnitrogen compound metabolic processregulation of biological qualityorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processanatomical structure developmentcellular developmental processresponse to stressresponse to external stimulusnitrogen compound metabolic processregulation of biological qualityorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processanatomical structure developmentcellular developmental processresponse to stressresponse to external stimulusnitrogen compound metabolic processregulation of biological qualityorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processanatomical structure developmentcellular developmental processresponse to stressresponse to external stimulusnitrogen compound metabolic processregulation of biological qualityorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processanatomical structure developmentcellular developmental processresponse to stressresponse to external stimulusnitrogen compound metabolic processregulation of biological qualityorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processanatomical structure developmentcellular developmental processresponse to stressresponse to external stimulusnitrogen compound metabolic processregulation of biological qualityorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular metabolic processanatomical structure developmentcellular developmental processresponse to stressresponse to external stimulusnitrogen compound metabolic processregulation of biological qualityorganic substance metabolic processmacromolecule macromolecule localizationestablishment establishment of localizationcellular metabcellular metabolic processanatomical stranatomical structure developmentcellular develcellular developmental processresponse to stresponse to stressresponse to exresponse to external stimulusnitrogen componitrogen compound metabolic processregulation of regulation of biological qualityorganic substaorganic substance metabolic process
cellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellcellmembranemembraneorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0042743 hydrogen peroxide metabolic process IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0050727 regulation of inflammatory response IEA
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process IEA
 biological_processGO:2000609 regulation of thyroid hormone generation IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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