ENSG00000141431
Homo sapiens domain protein asx-like ASXL3 asx transcription dna-templated binding severe hb asxl restriction endonuclease hth polycomb phd homology regulation nucleus dna metal ion nares anteverted arched eyebrows postnatal growth retardation global developmental
Features See expression report in BioGPS See gene description in Wikigenes See gene description in GeneCards See co-cited genes in PubMed Ortholog prediction (from Ensembl )Paralog prediction (from Ensembl ) ASXL1 / Q8IXJ9 / additional sex combs like 1, transcriptional regulator ENSG00000171456 20 ASXL2 / Q76L83 / additional sex combs like 2, transcriptional regulator ENSG00000143970 13
Protein motifs (from Interpro )Gene Ontology (GO ) nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic nitrogen compound metabolic process biosynthetic processbiosynthetic process cellular metabolic processcellular metabolic process primary metabolic processprimary metabolic process organic substance metabolic organic substance metabolic process organic cyclic compound binding heterocyclic compound binding ion binding organic cyclic compound binding heterocyclic compound binding ion binding organic cyclic compound binding heterocyclic compound binding ion binding organic cyclic compound binding heterocyclic compound binding ion binding organic cyclic compound binding heterocyclic compound binding ion binding organic cyclic compound binding heterocyclic compound binding ion binding organic cyclic compound binding heterocyclic compound binding ion binding organic cyclic compound binding heterocyclic compound binding ion binding organic cyclic compound binding heterocyclic compound binding ion binding organic cyclic compound binding heterocyclic compound binding ion binding organic cyclic compound bindingorganic cyclic compound binding heterocyclic compound bindingheterocyclic compound binding ion bindingion binding cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cellcell organelleorganelle
Pathways (from Reactome )No match Phenotype (from MGI , Zfin or HPO ) Head and neck abnormality Integument abnormality Growth abnormality Neurological abnormality Abnormality of the digestive system Head and neck abnormality Integument abnormality Growth abnormality Neurological abnormality Abnormality of the digestive system Head and neck abnormality Integument abnormality Growth abnormality Neurological abnormality Abnormality of the digestive system Head and neck abnormality Integument abnormality Growth abnormality Neurological abnormality Abnormality of the digestive system Head and neck abnormality Integument abnormality Growth abnormality Neurological abnormality Abnormality of the digestive system Head and neck abnormality Integument abnormality Growth abnormality Neurological abnormality Abnormality of the digestive system Head and neck abnormality Integument abnormality Growth abnormality Neurological abnormality Abnormality of the digestive system Head and neck abnormality Integument abnormality Growth abnormality Neurological abnormality Abnormality of the digestive system Head and neck abnormality Integument abnormality Growth abnormality Neurological abnormality Abnormality of the digestive system Head and neck abnormality Integument abnormality Growth abnormality Neurological abnormality Abnormality of the digestive system Head and neck abnormalityHead and neck abnormality Integument abnormalityIntegument abnormality Growth abnormalityGrowth abnormality Neurological abnormalityNeurological abnormality Abnormality of the digestiveAbnormality of the digestive system HP:0000463 Nares, anteverted "Anteriorly-facing nostrils viewed with the head in the Frankfurt horizontal and the eyes of the observer level with the eyes of the subject." [pmid:19152422]
Show HP:0002553 Arched eyebrows
Show HP:0008850 Postnatal growth retardation, severe
Show HP:0011344 Severe global developmental delay "A severe delay in the achievement of motor or mental milestones in the domains of development of a child." [DDD:hvfirth]
Show HP:0011968 Feeding difficulties "Impaired ability to eat related to problems gathering food and getting ready to suck, chew, or swallow it." [ISCA:eriggs]
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Interacting proteins (from Reactome )No match
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