ENSG00000142684


Homo sapiens
bindingZNF593zincfingerrnatranscriptionchlargesubunitregulationpolymeraseiidna-typeribosomalnucleusdna-templatedsequence-specificionmatrinu-c-likedouble-strandedsuperfamilyexportregulatoryregionnucleoluspreribosomeprecursor

Features
Gene ID: ENSG00000142684
  
Biological name :ZNF593
  
Synonyms : O00488 / zinc finger protein 593 / ZNF593
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.11
Gene start: 26169871
Gene end: 26170873
  
Corresponding Affymetrix probe sets: 204175_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000270812
Ensembl peptide - ENSP00000363384
NCBI entrez gene - 51042     See in Manteia.
OMIM - 616698
RefSeq - NM_015871
RefSeq - XM_017001398
RefSeq Peptide - NP_056955
swissprot - A9J4F5
swissprot - O00488
Ensembl - ENSG00000142684
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 znf593ENSDARG00000044102Danio rerio
 ZNF593ENSGALG00000000542Gallus gallus
 Q9DB42ENSMUSG00000028840Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003604  Matrin/U1-C-like, C2H2-type zinc finger
 IPR013087  Zinc finger C2H2-type
 IPR022755  Zinc finger, double-stranded RNA binding
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
macromolecule localizationcellular component biogenesisestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functionmacromolecule localizationcellular component biogenesisestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functionmacromolecule localizationcellular component biogenesisestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functionmacromolecule localizationcellular component biogenesisestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functionmacromolecule localizationcellular component biogenesisestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functionmacromolecule localizationcellular component biogenesisestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functionmacromolecule localizationcellular component biogenesisestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functionmacromolecule localizationcellular component biogenesisestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functionmacromolecule localizationcellular component biogenesisestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functionmacromolecule localizationcellular component biogenesisestablishment of localizationcellular localizationprotein-containing complex localizationnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processregulation of molecular functionmacromoleculmacromolecule localizationcellular comcellular component biogenesisestablishmenestablishment of localizationcellular loccellular localizationprotein-contprotein-containing complex localizationnitrogen comnitrogen compound metabolic processbiosyntheticbiosynthetic processcellular metcellular metabolic processprimary metaprimary metabolic processorganic subsorganic substance metabolic processregulation oregulation of molecular function
DNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingprotein bindingion bindingprotein-containing complex bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingprotein bindingion bindingprotein-containing complex bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingprotein bindingion bindingprotein-containing complex bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingprotein bindingion bindingprotein-containing complex bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingprotein bindingion bindingprotein-containing complex bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingprotein bindingion bindingprotein-containing complex bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingprotein bindingion bindingprotein-containing complex bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingprotein bindingion bindingprotein-containing complex bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingprotein bindingion bindingprotein-containing complex bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingprotein bindingion bindingprotein-containing complex bindingDNA-binding transcriptiDNA-binding transcription factor activityorganic cyclic compoundorganic cyclic compound bindingheterocyclic compound bheterocyclic compound bindingprotein bindingprotein bindingion bindingion bindingprotein-containing compprotein-containing complex binding
cellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellorganellemembrane-enclosed lumenprotein-containing complexcellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0000055 ribosomal large subunit export from nucleus IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IGI
 biological_processGO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding IGI
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0030687 preribosome, large subunit precursor IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IMP
 molecular_functionGO:0043023 ribosomal large subunit binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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