ENSG00000143164


Homo sapiens

Features
Gene ID: ENSG00000143164
  
Biological name :DCAF6
  
Synonyms : DCAF6 / DDB1 and CUL4 associated factor 6 / Q58WW2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q24.2
Gene start: 167935783
Gene end: 168075843
  
Corresponding Affymetrix probe sets: 217908_s_at (Human Genome U133 Plus 2.0 Array)   232349_x_at (Human Genome U133 Plus 2.0 Array)   241209_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356814
Ensembl peptide - ENSP00000396238
Ensembl peptide - ENSP00000432304
Ensembl peptide - ENSP00000311949
Ensembl peptide - ENSP00000356817
NCBI entrez gene - 55827     See in Manteia.
OMIM - 610494
RefSeq - XM_017001781
RefSeq - NM_001017977
RefSeq - NM_001198956
RefSeq - NM_001198957
RefSeq - NM_001349778
RefSeq - NM_001349779
RefSeq - NM_018442
RefSeq - XM_005245331
RefSeq - XM_005245332
RefSeq - XM_005245333
RefSeq - XM_017001779
RefSeq - XM_017001780
RefSeq Peptide - NP_001336708
RefSeq Peptide - NP_001336707
RefSeq Peptide - NP_060912
RefSeq Peptide - NP_001017977
RefSeq Peptide - NP_001185885
RefSeq Peptide - NP_001185886
swissprot - Q58WW2
swissprot - F2Z305
Ensembl - ENSG00000143164
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dcaf6ENSDARG00000078311Danio rerio
 DCAF6ENSGALG00000015435Gallus gallus
 Dcaf6ENSMUSG00000026571Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WDTC1 / Q8N5D0 / WD and tetratricopeptide repeats 1ENSG0000014278419
DCAF8 / Q5TAQ9 / DDB1 and CUL4 associated factor 8ENSG0000013271616
AL139011.2ENSG0000025846516
P0C7V8 / DCAF8L2 / DDB1 and CUL4 associated factor 8 like 2ENSG0000018918615
A6NGE4 / DCAF8L1 / DDB1 and CUL4 associated factor 8 like 1ENSG0000022637215


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IGI
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005925 focal adhesion IDA
 cellular_componentGO:0080008 Cul4-RING E3 ubiquitin ligase complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030374 nuclear receptor transcription coactivator activity IDA


Pathways (from Reactome)
Pathway description
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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