ENSG00000143515


Homo sapiens

Features
Gene ID: ENSG00000143515
  
Biological name :ATP8B2
  
Synonyms : ATP8B2 / ATPase phospholipid transporting 8B2 / P98198
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q21.3
Gene start: 154325553
Gene end: 154351307
  
Corresponding Affymetrix probe sets: 216873_s_at (Human Genome U133 Plus 2.0 Array)   226771_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357472
Ensembl peptide - ENSP00000357475
NCBI entrez gene - 57198     See in Manteia.
OMIM - 605867
RefSeq - XM_017001872
RefSeq - NM_001005855
RefSeq - NM_020452
RefSeq - XM_005245355
RefSeq - XM_005245356
RefSeq - XM_017001871
RefSeq Peptide - NP_065185
RefSeq Peptide - NP_001005855
swissprot - P98198
Ensembl - ENSG00000143515
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATP8B2ENSGALG00000034501Gallus gallus
 Atp8b2ENSMUSG00000060671Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATP8B4 / Q8TF62 / ATPase phospholipid transporting 8B4 (putative)ENSG0000010404369
ATP8B1 / O43520 / ATPase phospholipid transporting 8B1ENSG0000008192352
ATP8B3 / O60423 / ATPase phospholipid transporting 8B3ENSG0000013027043
ATP8A1 / Q9Y2Q0 / ATPase phospholipid transporting 8A1ENSG0000012440638
ATP8A2 / Q9NTI2 / ATPase phospholipid transporting 8A2ENSG0000013293238
ATP10D / Q9P241 / ATPase phospholipid transporting 10D (putative)ENSG0000014524635
ATP10A / O60312 / ATPase phospholipid transporting 10A (putative)ENSG0000020619035
ATP11B / Q9Y2G3 / ATPase phospholipid transporting 11B (putative)ENSG0000005806332
ATP11A / P98196 / ATPase phospholipid transporting 11AENSG0000006865031
ATP11C / Q8NB49 / ATPase phospholipid transporting 11CENSG0000010197430


Protein motifs (from Interpro)
Interpro ID Name
 IPR001757  P-type ATPase
 IPR006539  P-type ATPase, subfamily IV
 IPR008250  P-type ATPase, A domain superfamily
 IPR018303  P-type ATPase, phosphorylation site
 IPR023298  P-type ATPase, transmembrane domain superfamily
 IPR023299  P-type ATPase, cytoplasmic domain N
 IPR030347  Phospholipid-transporting ATPase ID
 IPR032630  P-type ATPase, C-terminal
 IPR032631  P-type ATPase, N-terminal
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0007030 Golgi organization IBA
 biological_processGO:0015914 phospholipid transport IEA
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0045332 phospholipid translocation IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004012 phospholipid-translocating ATPase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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