ENSG00000146809


Homo sapiens
domainproteinASB15ankyrinsocsrepeat-containingsuperfamilyubiquitinationubiquitinligasebindingboxrepeatbox-likeintracellularsignaltransductionpost-translationalmodificationcomplexnucleuscytoplasmcytosolubiquitin-proteintransferaseactivityneddylationantigenprocessingproteasomedegradation

Features
Gene ID: ENSG00000146809
  
Biological name :ASB15
  
Synonyms : ankyrin repeat and SOCS box containing 15 / ASB15 / Q8WXK1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q31.32
Gene start: 123567010
Gene end: 123639481
  
Corresponding Affymetrix probe sets: 1564679_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000406163
Ensembl peptide - ENSP00000416433
Ensembl peptide - ENSP00000438643
Ensembl peptide - ENSP00000275699
Ensembl peptide - ENSP00000390963
Ensembl peptide - ENSP00000397655
Ensembl peptide - ENSP00000401166
NCBI entrez gene - 142685     See in Manteia.
RefSeq - XM_017011757
RefSeq - XM_011515817
RefSeq - XM_011515818
RefSeq - XM_011515819
RefSeq - XM_011515820
RefSeq - XM_011515821
RefSeq - XM_017011756
RefSeq - NM_001290258
RefSeq - NM_080928
RefSeq - XM_005250146
RefSeq - XM_011515816
RefSeq Peptide - NP_001277187
RefSeq Peptide - NP_563616
swissprot - C9J956
swissprot - Q8WXK1
swissprot - A0A0C4DG46
swissprot - Q7Z4V1
Ensembl - ENSG00000146809
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 asb15aENSDARG00000045633Danio rerio
 asb15bENSDARG00000045863Danio rerio
 ASB15ENSGALG00000008814Gallus gallus
 Asb15ENSMUSG00000029685Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASB14 / A6NK59 / ankyrin repeat and SOCS box containing 14ENSG0000023938851
ASB2 / Q96Q27 / ankyrin repeat and SOCS box containing 2ENSG0000010062832
ASB3 / Q9Y575 / ankyrin repeat and SOCS box containing 3ENSG0000011523925
GPR75-ASB3 / GPR75-ASB3 readthroughENSG0000027089825
ASB5 / Q8WWX0 / ankyrin repeat and SOCS box containing 5ENSG0000016412216
ASB9 / Q96DX5 / ankyrin repeat and SOCS box containing 9ENSG0000010204814
ASB11 / Q8WXH4 / ankyrin repeat and SOCS box containing 11ENSG0000016519214
ASB1 / Q9Y576 / ankyrin repeat and SOCS box containing 1ENSG0000006580213
ASB7 / Q9H672 / ankyrin repeat and SOCS box containing 7ENSG0000018347512
ASB13 / Q8WXK3 / ankyrin repeat and SOCS box containing 13ENSG0000019637212
ASB12 / Q8WXK4 / ankyrin repeat and SOCS box containing 12ENSG0000019888112


Protein motifs (from Interpro)
Interpro ID Name
 IPR001496  SOCS box domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR036036  SOCS box-like domain superfamily
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusnitrogen compound metabnitrogen compound metabolic processcellular metabolic proccellular metabolic processprimary metabolic proceprimary metabolic processorganic substance metaborganic substance metabolic processcell communicationcell communicationcellular response to stcellular response to stimulus
catalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteintransferase activityprotein bindingcatalytic activity, acting on a proteincatalytic activity, acting on a proteintransferase activitytransferase activityprotein bindingprotein binding
cellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellcellprotein-containing complexprotein-containing complexorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0000151 ubiquitin ligase complex IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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