ENSG00000147896


Homo sapiens

Features
Gene ID: ENSG00000147896
  
Biological name :IFNK
  
Synonyms : IFNK / interferon kappa / Q9P0W0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: p21.2
Gene start: 27524314
Gene end: 27526498
  
Corresponding Affymetrix probe sets: 224093_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000276943
NCBI entrez gene - 56832     See in Manteia.
OMIM - 615326
RefSeq - NM_020124
RefSeq Peptide - NP_064509
swissprot - Q9P0W0
Ensembl - ENSG00000147896
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000015062Gallus gallus
 IfnkENSMUSG00000042993Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IFNW1 / P05000 / interferon omega 1ENSG0000017704730
IFNA8 / P32881 / interferon alpha 8ENSG0000012024229
IFNA16 / P05015 / interferon alpha 16ENSG0000014788529
IFNA1 / P01562 / interferon alpha 1ENSG0000019791929
IFNA14 / P01570 / interferon alpha 14ENSG0000022808329
IFNA13 / P01562 / interferon alpha 13ENSG0000023381629
IFNA17 / P01571 / interferon alpha 17ENSG0000023482929
IFNA6 / P05013 / interferon alpha 6ENSG0000012023528
IFNA21 / P01568 / interferon alpha 21ENSG0000013708028
IFNA5 / P01569 / interferon alpha 5ENSG0000014787328
IFNA10 / P01566 / interferon alpha 10ENSG0000018680328
IFNA2 / P01563 / interferon alpha 2ENSG0000018837928
IFNA4 / P05014 / interferon alpha 4ENSG0000023663728
IFNA7 / P01567 / interferon alpha 7ENSG0000021404227


Protein motifs (from Interpro)
Interpro ID Name
 IPR000471  Interferon alpha/beta/delta
 IPR009079  Four-helical cytokine-like, core


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IBA
 biological_processGO:0002286 T cell activation involved in immune response IBA
 biological_processGO:0002323 natural killer cell activation involved in immune response IBA
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006952 defense response IEA
 biological_processGO:0006959 humoral immune response IBA
 biological_processGO:0008285 negative regulation of cell proliferation NAS
 biological_processGO:0009615 response to virus IEP
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IDA
 biological_processGO:0030101 natural killer cell activation NAS
 biological_processGO:0030183 B cell differentiation IBA
 biological_processGO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein IBA
 biological_processGO:0042100 B cell proliferation IBA
 biological_processGO:0043330 response to exogenous dsRNA IBA
 biological_processGO:0045089 positive regulation of innate immune response TAS
 biological_processGO:0051607 defense response to virus IEA
 cellular_componentGO:0005576 extracellular region IC
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005126 cytokine receptor binding IEA
 molecular_functionGO:0005132 type I interferon receptor binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr