ENSG00000149452


Homo sapiens

Features
Gene ID: ENSG00000149452
  
Biological name :SLC22A8
  
Synonyms : Q8TCC7 / SLC22A8 / solute carrier family 22 member 8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q12.3
Gene start: 62989154
Gene end: 63015839
  
Corresponding Affymetrix probe sets: 221298_s_at (Human Genome U133 Plus 2.0 Array)   231352_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000337335
Ensembl peptide - ENSP00000441658
Ensembl peptide - ENSP00000443368
Ensembl peptide - ENSP00000311463
Ensembl peptide - ENSP00000398548
NCBI entrez gene - 9376     See in Manteia.
OMIM - 607581
RefSeq - XM_011545364
RefSeq - NM_001184732
RefSeq - NM_001184733
RefSeq - NM_001184736
RefSeq - NM_004254
RefSeq Peptide - NP_001171661
RefSeq Peptide - NP_001171662
RefSeq Peptide - NP_001171665
RefSeq Peptide - NP_004245
swissprot - Q8TCC7
swissprot - H7BXN9
Ensembl - ENSG00000149452
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 oatxENSDARG00000019713Danio rerio
 slc22a6lENSDARG00000055523Danio rerio
 O88909ENSMUSG00000063796Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q4U2R8 / SLC22A6 / solute carrier family 22 member 6ENSG0000019790151
Q9NSA0 / SLC22A11 / solute carrier family 22 member 11ENSG0000016806542
Q96S37 / SLC22A12 / solute carrier family 22 member 12ENSG0000019789142
Q8N4F4 / SLC22A24 / solute carrier family 22 member 24ENSG0000019765839
Q63ZE4 / SLC22A10 / solute carrier family 22 member 10ENSG0000018499938
Q9Y694 / SLC22A7 / solute carrier family 22 member 7ENSG0000013720437
Q8IVM8 / SLC22A9 / solute carrier family 22 member 9ENSG0000014974237
Q6T423 / SLC22A25 / solute carrier family 22 member 25ENSG0000019660036
O15244 / SLC22A2 / solute carrier family 22 member 2ENSG0000011249933
O15245 / SLC22A1 / solute carrier family 22 member 1ENSG0000017500333
O75751 / SLC22A3 / solute carrier family 22 member 3ENSG0000014647732
Q9Y226 / SLC22A13 / solute carrier family 22 member 13ENSG0000017294032
O76082 / SLC22A5 / solute carrier family 22 member 5ENSG0000019737532
Q8IZD6 / SLC22A15 / solute carrier family 22 member 15ENSG0000016339330
Q9H015 / SLC22A4 / solute carrier family 22 member 4ENSG0000019720830
Q9Y267 / SLC22A14 / solute carrier family 22 member 14ENSG0000014467128
Q86VW1 / SLC22A16 / solute carrier family 22 member 16ENSG0000000480927


Protein motifs (from Interpro)
Interpro ID Name
 IPR004749  Organic cation transport protein/SVOP
 IPR005828  Major facilitator, sugar transporter-like
 IPR005829  Sugar transporter, conserved site
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0015698 inorganic anion transport IEA
 biological_processGO:0043252 sodium-independent organic anion transport IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0098656 anion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0005452 inorganic anion exchanger activity IDA
 molecular_functionGO:0015301 anion:anion antiporter activity TAS
 molecular_functionGO:0015347 sodium-independent organic anion transmembrane transporter activity IBA
 molecular_functionGO:0022857 transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Organic anion transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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