ENSG00000149806


Homo sapiens
ribosomalcomplexFAUproteinsresponsetranslationubiquitindecaymediatedsubunitformationdomainmrnaprocessimmunerrnaprocessingtranslationalinitiationsrp-dependentcotranslationaltargetingmembraneviralhumoralantimicrobialpeptidecytosolribosomesmall

Features
Gene ID: ENSG00000149806
  
Biological name :FAU
  
Synonyms : FAU / FAU, ubiquitin like and ribosomal protein S30 fusion / P35544 / P62861
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q13.1
Gene start: 65120628
Gene end: 65122473
  
Corresponding Affymetrix probe sets: 200019_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433139
Ensembl peptide - ENSP00000434440
Ensembl peptide - ENSP00000436110
Ensembl peptide - ENSP00000435370
Ensembl peptide - ENSP00000434680
Ensembl peptide - ENSP00000279259
Ensembl peptide - ENSP00000413848
Ensembl peptide - ENSP00000431822
NCBI entrez gene - 2197     See in Manteia.
OMIM - 134690
RefSeq - NM_001997
RefSeq Peptide - NP_001988
swissprot - E9PM49
swissprot - J3KN89
swissprot - P35544
swissprot - E9PR30
swissprot - P62861
swissprot - E9PMS9
Ensembl - ENSG00000149806
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fauaENSDARG00000099022Danio rerio
 faubENSDARG00000043663Danio rerio
 FauENSMUSG00000038274Mus musculus
 Gm9843ENSMUSG00000050299Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR006846  Ribosomal protein S30
 IPR019954  Ubiquitin conserved site
 IPR019956  Ubiquitin
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
nitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responsecellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsresponse to external stimulusresponse to biotic stimulusnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responsecellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsresponse to external stimulusresponse to biotic stimulusnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responsecellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsresponse to external stimulusresponse to biotic stimulusnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responsecellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsresponse to external stimulusresponse to biotic stimulusnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responsecellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsresponse to external stimulusresponse to biotic stimulusnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responsecellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsresponse to external stimulusresponse to biotic stimulusnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responsecellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsresponse to external stimulusresponse to biotic stimulusnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responsecellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsresponse to external stimulusresponse to biotic stimulusnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responsecellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsresponse to external stimulusresponse to biotic stimulusnitrogen compound metabolic processcatabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to stressimmune responsecellular component biogenesisbiosynthetic processmacromolecule localizationestablishment of localizationcellular localizationinterspecies interaction between organismsresponse to external stimulusresponse to biotic stimulusnitrogen nitrogen compound metabolic processcataboliccatabolic processcellular cellular metabolic processprimary mprimary metabolic processorganic sorganic substance metabolic processresponse response to stressimmune reimmune responsecellular cellular component biogenesisbiosynthebiosynthetic processmacromolemacromolecule localizationestablishestablishment of localizationcellular cellular localizationinterspecinterspecies interaction between organismsresponse response to external stimulusresponse response to biotic stimulus
organic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeprotein bindingorganic cyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomestructural constituent of ribosomeprotein bindingprotein binding
extracellular regioncellorganellemembrane-enclosed lumenprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenprotein-containing complexextracellular regioncellorganellemembrane-enclosed lumenprotein-containing complexextracellular regionextracellular regioncellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumenprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0002227 innate immune response in mucosa IDA
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0008150 biological_process ND
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0019731 antibacterial humoral response IDA
 biological_processGO:0050830 defense response to Gram-positive bacterium IDA
 biological_processGO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide IDA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0015935 small ribosomal subunit HDA
 cellular_componentGO:0022627 cytosolic small ribosomal subunit IDA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003735 structural constituent of ribosome IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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