ENSG00000150977


Homo sapiens
proteinRILPL2domainmembranebindingdimerizationrhcelltransportciliumciliaryrabinteractinglysosomalepithelialmorphogenesisassemblyplasmacytoplasmcentrosomemicrotubuleorganizingcentercytosolcytoskeletonbasalbodyprojectionextracellularexosomesmall

Features
Gene ID: ENSG00000150977
  
Biological name :RILPL2
  
Synonyms : Q969X0 / Rab interacting lysosomal protein like 2 / RILPL2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.31
Gene start: 123410683
Gene end: 123436717
  
Corresponding Affymetrix probe sets: 227983_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000280571
NCBI entrez gene - 196383     See in Manteia.
OMIM - 614093
RefSeq - NM_145058
RefSeq - XM_017018959
RefSeq Peptide - NP_659495
swissprot - Q969X0
Ensembl - ENSG00000150977
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A4IGC3ENSDARG00000024818Danio rerio
 RILPL2ENSGALG00000003321Gallus gallus
 Q99LE1ENSMUSG00000029401Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5EBL4 / RILPL1 / Rab interacting lysosomal protein like 1ENSG0000018802629
RILP / Q96NA2 / Rab interacting lysosomal proteinENSG0000016770519


Protein motifs (from Interpro)
Interpro ID Name
 IPR021563  Rab interacting lysosomal protein, dimerization domain
 IPR034743  RH1 domain
 IPR034744  RH2 domain


Gene Ontology (GO)
cellular component organizationanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationcellular component organizationanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationcellular component organizationanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationcellular component organizationanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationcellular component organizationanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationcellular component organizationanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationcellular component organizationanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationcellular component organizationanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationcellular component organizationanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationcellular component organizationanatomical structure developmentcellular developmental processmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationcellular component ocellular component organizationanatomical structureanatomical structure developmentcellular developmentcellular developmental processmacromolecule localimacromolecule localizationestablishment of locestablishment of localizationcellular component bcellular component biogenesiscellular localizatiocellular localization
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellcellorganelleorganellemembranemembraneextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0003382 epithelial cell morphogenesis IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0060271 cilium assembly IBA
 biological_processGO:1903445 protein transport from ciliary membrane to plasma membrane IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005929 cilium ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0036064 ciliary basal body IBA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0031267 small GTPase binding IBA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0051959 dynein light intermediate chain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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