ENSG00000152061


Homo sapiens
proteinRABGAP1Ldomaingtpaseregulationactivityrab-gtpase-tbcsuperfamilyrabtransportvesicleendosomemembranebindingptbpiph-likekinesin-likegtpase-activatingintracellularendocytosiscellcyclefusionlocalizationactivationnucleusearlygolgiapparatuscilium

Features
Gene ID: ENSG00000152061
  
Biological name :RABGAP1L
  
Synonyms : B7ZAP0 / Q5R372 / RABGAP1L / RAB GTPase activating protein 1 like
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q25.1
Gene start: 174159410
Gene end: 174995308
  
Corresponding Affymetrix probe sets: 1554725_at (Human Genome U133 Plus 2.0 Array)   203020_at (Human Genome U133 Plus 2.0 Array)   213982_s_at (Human Genome U133 Plus 2.0 Array)   215342_s_at (Human Genome U133 Plus 2.0 Array)   232702_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000403136
Ensembl peptide - ENSP00000420660
Ensembl peptide - ENSP00000489605
Ensembl peptide - ENSP00000489232
Ensembl peptide - ENSP00000489213
Ensembl peptide - ENSP00000489188
Ensembl peptide - ENSP00000489163
Ensembl peptide - ENSP00000435911
Ensembl peptide - ENSP00000434600
Ensembl peptide - ENSP00000432734
Ensembl peptide - ENSP00000432490
Ensembl peptide - ENSP00000251507
Ensembl peptide - ENSP00000281844
Ensembl peptide - ENSP00000318603
Ensembl peptide - ENSP00000350027
Ensembl peptide - ENSP00000356660
Ensembl peptide - ENSP00000356661
Ensembl peptide - ENSP00000375916
NCBI entrez gene - 9910     See in Manteia.
OMIM - 609238
RefSeq - NM_014857
RefSeq - XM_017002999
RefSeq - XM_017002998
RefSeq - XM_017002997
RefSeq - XM_017002996
RefSeq - XM_017002995
RefSeq - XM_017002994
RefSeq - XM_011510223
RefSeq - XM_006711693
RefSeq - XM_005245681
RefSeq - XM_005245680
RefSeq - NM_001035230
RefSeq - NM_001243763
RefSeq - NM_001243764
RefSeq - NM_001243765
RefSeq Peptide - NP_001030307
RefSeq Peptide - NP_001230692
RefSeq Peptide - NP_001230693
RefSeq Peptide - NP_001230694
RefSeq Peptide - NP_001317918
RefSeq Peptide - NP_055672
swissprot - E9PNV2
swissprot - Q5R372
swissprot - F5H8L0
swissprot - F1LJ00
swissprot - A0A0C4DG54
swissprot - A0A0U1RQT5
swissprot - A0A0U1RQV7
swissprot - E9PS63
swissprot - A0A0U1RQX4
swissprot - A0A0U1RQY6
swissprot - A0A0U1RRM5
swissprot - B7ZAP0
Ensembl - ENSG00000152061
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rabgap1l2ENSDARG00000060315Danio rerio
 RABGAP1LENSGALG00000004578Gallus gallus
 A6H6A9ENSMUSG00000026721Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Y3P9 / RABGAP1 / RAB GTPase activating protein 1ENSG0000001145465
Q86TI0 / TBC1D1 / TBC1 domain family member 1ENSG0000006588224
O60343 / TBC1D4 / TBC1 domain family member 4ENSG0000013611124
EVI5 / O60447 / ecotropic viral integration site 5ENSG0000006720819
EVI5L / Q96CN4 / ecotropic viral integration site 5 likeENSG0000014245917
Q9P2M4 / TBC1D14 / TBC1 domain family member 14ENSG0000013240515
O60347 / TBC1D12 / TBC1 domain family member 12ENSG0000010823913


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR022164  Kinesin-like
 IPR033185  Rab GTPase-activating protein 1
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
macromolecule localizationestablishment of localizationcellular localizationcell cyclecellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcell cyclecellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcell cyclecellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcell cyclecellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcell cyclecellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcell cyclecellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcell cyclecellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcell cyclecellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcell cyclecellular component organizationregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationcell cyclecellular component organizationregulation of molecular functionmacromolecule localizatmacromolecule localizationestablishment of localiestablishment of localizationcellular localizationcellular localizationcell cyclecell cyclecellular component orgacellular component organizationregulation of molecularregulation of molecular function
enzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityprotein bindingenzyme regulator activityenzyme regulator activityprotein bindingprotein binding
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0032880 regulation of protein localization IDA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005929 cilium IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017137 Rab GTPase binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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