ENSG00000155886


Homo sapiens

Features
Gene ID: ENSG00000155886
  
Biological name :SLC24A2
  
Synonyms : Q9UI40 / SLC24A2 / solute carrier family 24 member 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: p22.1
Gene start: 19507452
Gene end: 19786928
  
Corresponding Affymetrix probe sets: 220867_s_at (Human Genome U133 Plus 2.0 Array)   229110_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000286344
Ensembl peptide - ENSP00000344801
NCBI entrez gene - 25769     See in Manteia.
OMIM - 609838
RefSeq - XM_017014593
RefSeq - NM_001193288
RefSeq - NM_020344
RefSeq - XM_005251426
RefSeq - XM_006716750
RefSeq - XM_017014592
RefSeq - XM_005251425
RefSeq Peptide - NP_065077
RefSeq Peptide - NP_001180217
swissprot - Q9UI40
Ensembl - ENSG00000155886
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01081780.1ENSDARG00000063158Danio rerio
 slc24a2ENSDARG00000042988Danio rerio
 SLC24A2ENSGALG00000015080Gallus gallus
 Slc24a2ENSMUSG00000037996Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O60721 / SLC24A1 / solute carrier family 24 member 1ENSG0000007462156
Q9HC58 / SLC24A3 / solute carrier family 24 member 3ENSG0000018505234
Q8NFF2 / SLC24A4 / solute carrier family 24 member 4ENSG0000014009033
Q71RS6 / SLC24A5 / solute carrier family 24 member 5ENSG0000018846726
Q6J4K2 / SLC8B1 / solute carrier family 8 member B1ENSG0000008906020


Protein motifs (from Interpro)
Interpro ID Name
 IPR004481  Sodium/potassium/calcium exchanger
 IPR004837  Sodium/calcium exchanger membrane region
 IPR030236  Sodium/potassium/calcium exchanger 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport TAS
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IBA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0007612 learning IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0034220 ion transmembrane transport IDA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060291 long-term synaptic potentiation IBA
 biological_processGO:0060292 long term synaptic depression IBA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031226 intrinsic component of plasma membrane IEA
 molecular_functionGO:0005262 calcium channel activity IBA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0008273 calcium, potassium:sodium antiporter activity IDA
 molecular_functionGO:0015293 symporter activity IEA
 molecular_functionGO:0015297 antiporter activity IEA
 molecular_functionGO:0016151 nickel cation binding IEA
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0030955 potassium ion binding IBA
 molecular_functionGO:0031402 sodium ion binding IBA
 molecular_functionGO:0046870 cadmium ion binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
Sodium/Calcium exchangers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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