ENSG00000157823


Homo sapiens
transportAP3S2complexproteinadaptorvesiclemembranesigmasubunitintracellularanterogradecytoplasmicclathrinsmallchainlongin-likedomainsuperfamilyapmuaxonalvesicle-mediatedsynapticgolgiapparatuscoatap-membrane-boundedorganelleaxoncytoplasm

Features
Gene ID: ENSG00000157823
  
Biological name :AP3S2
  
Synonyms : adaptor related protein complex 3 sigma 2 subunit / AP3S2 / P59780
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q26.1
Gene start: 89830599
Gene end: 89894638
  
Corresponding Affymetrix probe sets: 202398_at (Human Genome U133 Plus 2.0 Array)   202399_s_at (Human Genome U133 Plus 2.0 Array)   213215_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453380
Ensembl peptide - ENSP00000481434
Ensembl peptide - ENSP00000454027
Ensembl peptide - ENSP00000453852
Ensembl peptide - ENSP00000338777
Ensembl peptide - ENSP00000394170
Ensembl peptide - ENSP00000452862
Ensembl peptide - ENSP00000453223
Ensembl peptide - ENSP00000453288
NCBI entrez gene - 10239     See in Manteia.
OMIM - 602416
RefSeq - NM_005829
RefSeq Peptide - NP_005820
swissprot - H0YLI7
swissprot - H0YLX6
swissprot - H0YN38
swissprot - H0YNI6
swissprot - A0A087WY05
swissprot - P59780
swissprot - A0A024RC62
swissprot - H0YKM3
Ensembl - ENSG00000157823
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ap3s2ENSDARG00000039882Danio rerio
 AP3S2ENSGALG00000008291Gallus gallus
 Ap3s2ENSMUSG00000063801Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AP3S1 / Q92572 / adaptor related protein complex 3 sigma 1 subunitENSG0000017787983


Protein motifs (from Interpro)
Interpro ID Name
 IPR000804  Clathrin adaptor complex, small chain
 IPR011012  Longin-like domain superfamily
 IPR016635  Adaptor protein complex, sigma subunit
 IPR022775  AP complex, mu/sigma subunit


Gene Ontology (GO)
macromolecule localizationestablishment of localizationcellular localizationmovement of cell or subcellular componentmicrotubule-based processmacromolecule localizationestablishment of localizationcellular localizationmovement of cell or subcellular componentmicrotubule-based processmacromolecule localizationestablishment of localizationcellular localizationmovement of cell or subcellular componentmicrotubule-based processmacromolecule localizationestablishment of localizationcellular localizationmovement of cell or subcellular componentmicrotubule-based processmacromolecule localizationestablishment of localizationcellular localizationmovement of cell or subcellular componentmicrotubule-based processmacromolecule localizationestablishment of localizationcellular localizationmovement of cell or subcellular componentmicrotubule-based processmacromolecule localizationestablishment of localizationcellular localizationmovement of cell or subcellular componentmicrotubule-based processmacromolecule localizationestablishment of localizationcellular localizationmovement of cell or subcellular componentmicrotubule-based processmacromolecule localizationestablishment of localizationcellular localizationmovement of cell or subcellular componentmicrotubule-based processmacromolecule localizationestablishment of localizationcellular localizationmovement of cell or subcellular componentmicrotubule-based processmacromolecule localizationmacromolecule localizationestablishment of localizatioestablishment of localizationcellular localizationcellular localizationmovement of cell or subcellumovement of cell or subcellular componentmicrotubule-based processmicrotubule-based process
protein transporter activityprotein transporter activityprotein transporter activityprotein transporter activityprotein transporter activityprotein transporter activityprotein transporter activityprotein transporter activityprotein transporter activityprotein transporter activityprotein transporter activityprotein transporter activity
cellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellcellorganelleorganellemembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport TAS
 biological_processGO:0008089 anterograde axonal transport ISS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0048490 anterograde synaptic vesicle transport ISS
 cellular_componentGO:0005794 Golgi apparatus TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030117 membrane coat IEA
 cellular_componentGO:0030123 AP-3 adaptor complex IDA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:1904115 axon cytoplasm IEA
 molecular_functionGO:0008565 protein transporter activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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