ENSG00000158604


Homo sapiens
membraneTMED4signalendoplasmicreticulumgolddomaintmp-relatedtransductionproteintransportregulationi-kappabkinasenf-kappabsignalingintegralcomponentextracellularexosomeobsoletetransduceractivity

Features
Gene ID: ENSG00000158604
  
Biological name :TMED4
  
Synonyms : Q7Z7H5 / TMED4 / transmembrane p24 trafficking protein 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p13
Gene start: 44577894
Gene end: 44582287
  
Corresponding Affymetrix probe sets: 1558052_at (Human Genome U133 Plus 2.0 Array)   1558053_s_at (Human Genome U133 Plus 2.0 Array)   1558487_a_at (Human Genome U133 Plus 2.0 Array)   224676_at (Human Genome U133 Plus 2.0 Array)   224680_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000289577
Ensembl peptide - ENSP00000404042
Ensembl peptide - ENSP00000417443
NCBI entrez gene - 222068     See in Manteia.
OMIM - 612038
RefSeq - NM_001303061
RefSeq - NM_001303058
RefSeq - NM_001303059
RefSeq - NM_001303060
RefSeq - NM_001303062
RefSeq - NM_182547
RefSeq Peptide - NP_872353
RefSeq Peptide - NP_001289987
RefSeq Peptide - NP_001289988
RefSeq Peptide - NP_001289989
RefSeq Peptide - NP_001289990
RefSeq Peptide - NP_001289991
swissprot - F8W7F7
swissprot - Q7Z7H5
Ensembl - ENSG00000158604
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmed4ENSDARG00000024954Danio rerio
 Tmed4ENSMUSG00000004394Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TMED9 / Q9BVK6 / transmembrane p24 trafficking protein 9ENSG0000018484076


Protein motifs (from Interpro)
Interpro ID Name
 IPR009038  GOLD domain
 IPR015720  TMP21-related


Gene Ontology (GO)
cell communicationcellular response to stimulusmacromolecule localizationestablishment of localizationcell communicationcellular response to stimulusmacromolecule localizationestablishment of localizationcell communicationcellular response to stimulusmacromolecule localizationestablishment of localizationcell communicationcellular response to stimulusmacromolecule localizationestablishment of localizationcell communicationcellular response to stimulusmacromolecule localizationestablishment of localizationcell communicationcellular response to stimulusmacromolecule localizationestablishment of localizationcell communicationcellular response to stimulusmacromolecule localizationestablishment of localizationcell communicationcellular response to stimulusmacromolecule localizationestablishment of localizationcell communicationcellular response to stimulusmacromolecule localizationestablishment of localizationcell communicationcellular response to stimulusmacromolecule localizationestablishment of localizationcell communicationcell communicationcellular response to stimuluscellular response to stimulusmacromolecule localizationmacromolecule localizationestablishment of localizationestablishment of localization
cellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellorganellemembraneextracellular regioncellcellorganelleorganellemembranemembraneextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling HMP
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004871 obsolete signal transducer activity HMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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