ENSG00000158747


Homo sapiens

Features
Gene ID: ENSG00000158747
  
Biological name :NBL1
  
Synonyms : NBL1 / neuroblastoma 1, DAN family BMP antagonist / P41271
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.13
Gene start: 19596979
Gene end: 19658456
  
Corresponding Affymetrix probe sets: 201621_at (Human Genome U133 Plus 2.0 Array)   37005_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000394079
Ensembl peptide - ENSP00000399333
Ensembl peptide - ENSP00000483061
Ensembl peptide - ENSP00000480391
Ensembl peptide - ENSP00000478885
Ensembl peptide - ENSP00000478223
Ensembl peptide - ENSP00000473411
Ensembl peptide - ENSP00000449007
Ensembl peptide - ENSP00000412419
Ensembl peptide - ENSP00000400250
Ensembl peptide - ENSP00000289749
Ensembl peptide - ENSP00000364278
Ensembl peptide - ENSP00000390607
Ensembl peptide - ENSP00000391858
NCBI entrez gene - 100532736     See in Manteia.
NCBI entrez gene - 4681     See in Manteia.
OMIM - 600613
RefSeq - NM_001204089
RefSeq - NM_001278164
RefSeq - NM_001278165
RefSeq - NM_001278166
RefSeq - NM_005380
RefSeq - NM_182744
RefSeq - NM_001204084
RefSeq - NM_001204085
RefSeq - NM_001204088
RefSeq - NM_001204086
RefSeq Peptide - NP_001191015
RefSeq Peptide - NP_001191018
RefSeq Peptide - NP_001265093
RefSeq Peptide - NP_001265094
RefSeq Peptide - NP_001265095
RefSeq Peptide - NP_005371
RefSeq Peptide - NP_877421
RefSeq Peptide - NP_001191013
RefSeq Peptide - NP_001191014
RefSeq Peptide - NP_001191017
swissprot - P41271
swissprot - A3KFI5
swissprot - A3KFI4
swissprot - A3KFI3
swissprot - A3KFI2
swissprot - A3KFI1
swissprot - A0A087WTY6
swissprot - E5RFZ1
Ensembl - ENSG00000158747
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01085139.1ENSDARG00000102687Danio rerio
 NBL1ENSGALG00000040297Gallus gallus
 Nbl1ENSMUSG00000041120Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GREM2 / Q9H772 / gremlin 2, DAN family BMP antagonistENSG0000018087519
GREM1 / O60565 / gremlin 1, DAN family BMP antagonistENSG0000016692318


Protein motifs (from Interpro)
Interpro ID Name
 IPR004133  DAN
 IPR006207  Cystine knot, C-terminal
 IPR016728  Neuroblastoma suppressor of tumourigenicity 1
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007399 nervous system development ISS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IMP
 biological_processGO:0035582 sequestering of BMP in extracellular matrix ISS
 biological_processGO:0038098 sequestering of BMP from receptor via BMP binding IDA
 biological_processGO:0045666 positive regulation of neuron differentiation ISS
 biological_processGO:0048263 determination of dorsal identity ISS
 biological_processGO:0048812 neuron projection morphogenesis ISS
 biological_processGO:0090027 negative regulation of monocyte chemotaxis ISS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016015 morphogen activity ISS
 molecular_functionGO:0036122 BMP binding ISS
 molecular_functionGO:0042803 protein homodimerization activity IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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